(Q40743025)

23 September 2017

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title

Extrahepatic metabolism of drugs in humans (English)

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23 September 2017

D R Krishna

1

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PubMed ID

8162658

23 September 2017

U Klotz

series ordinal

2

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23 September 2017

1 February 1994

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Clinical Pharmacokinetics

23 September 2017

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23 September 2017

26

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23 September 2017

144-160

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23 September 2017

2

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https://scigraph.springernature.com/pub.10.2165/00003088-199426020-00007

23 September 2017

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Metabolism of isoprenaline in dog and man

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Propofol metabolism in man during the anhepatic and reperfusion phases of liver transplantation.

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Biotransformation of diflucortolone valerate in the skin of rat, guinea pig and man (author's transl)

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Characterization and kinetics of a microsomal UDP-glucuronate: testosterone-flucuronyltransferase in man

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12 December 2020

Glucuronidation of morphine in human kidney microsomes

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Uptake, release and metabolism of drugs in the lungs

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Metabolism rate of oxodipine in rats and humans: comparison of in vivo and in vitro data

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12 December 2020

Cutaneous metabolism of xenobiotics

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12 December 2020

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12 December 2020

Lung uptake of lidocaine in man as influenced by anaesthesia, mepivacaine infusion or lung insufficiency.

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12 December 2020

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12 December 2020

Stereoselective sulphate conjugation of salbutamol in humans: comparison of hepatic, intestinal and platelet activity.

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12 December 2020

Extrahepatic metabolism of zidovudine

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12 December 2020

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12 December 2020

First pass uptake of 14C-propranolol by the lung

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12 December 2020

Sulfation pharmacogenetics: correlation of human platelet and small intestinal phenol sulfotransferase

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12 December 2020

Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides.

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12 December 2020

Isosorbide dinitrate kinetics and dynamics after intravenous, sublingual, and percutaneous dosing in angina

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12 December 2020

Colonic N-acetylation of 5-aminosalicylic acid in inflammatory bowel disease

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12 December 2020

Sulfate conjugation of monoamines in human brain: purification and some properties of an arylamine sulfotransferase from cerebral cortex.

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12 December 2020

The immunocytochemical localisation and distribution of cytochrome P-450 in normal human hepatic and extrahepatic tissues with a monoclonal antibody to human cytochrome P-450

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12 December 2020

Interindividual variability in the N-sulphation of desipramine in human liver and platelets

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12 December 2020

Disposition of radiolabeled imipenem and cilastatin in normal human volunteers

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12 December 2020

Studies on sulphatases. 12. The arylsulphatases of human tissues

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12 December 2020

Immunohistochemical localization of cytochromes P450 with polyclonal and monoclonal antibodies

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12 December 2020

Human cytochromes P450: problems and prospects

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12 December 2020

Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism

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12 December 2020

Normal metabolism of morphine in cirrhosis

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12 December 2020

Gastric origin of the first-pass metabolism of ethanol in humans: effect of gastrectomy

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12 December 2020

Cardio-pulmonary elimination of 5-fluorouracil after bolus injection in the hepatic artery

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12 December 2020

Phenacetin concentrations in portal and hepatic venous blood in man

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12 December 2020

Sulfate conjugation of neurotransmitters and drugs. Introduction

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12 December 2020

Portal levels and hepatic clearance of 5-fluorouracil after intraperitoneal administration in humans

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12 December 2020

The pharmacokinetics of oxpentifylline in man when administered by constant intravenous infusion

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12 December 2020

Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5?-diphosphoglucuronic acid in human tissues

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12 December 2020

Xenobiotic metabolism in human brain--presence of cytochrome P-450 and associated mono-oxygenases.

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12 December 2020

Pharmacokinetic implications for the clinical use of propofol

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12 December 2020

Pharmacokinetics of flestolol in man: preliminary data

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12 December 2020

Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors

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12 December 2020

First-pass metabolism of cyclosporin by the gut

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12 December 2020

Extrahepatic metabolism of morphine occurs in humans

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12 December 2020

Profile of drug-metabolizing enzymes in human ileum and colon

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12 December 2020

Tissue distribution of drug-metabolizing enzymes in humans

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12 December 2020

Pharmacokinetics of intravenous and oral pentoxifylline in healthy volunteers and in cirrhotic patients

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12 December 2020

Investigation into the species-specific deacylation of penta-acetyl-gitoxin

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12 December 2020

Comparative study of human intestinal and hepatic esterases as related to enzymatic properties and hydrolizing activity for ester-type drugs

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12 December 2020

Pharmacokinetics of methysergide and its metabolite methylergometrine in man

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12 December 2020

Biotransformation enzymes in human intestine: critical low levels in the colon?

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12 December 2020

Linear pharmacokinetics of intravenous ergotamine tartrate

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12 December 2020

Metabolic transformations of cortisol-4-[14C] in human skin

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12 December 2020

The partial purification and properties of a human erythrocyte 4-nitroacetophenone reductase

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12 December 2020

Microsomal cytochrome P450 in human brain regions

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12 December 2020

Intestinal glutathione transport system: a possible detoxication role

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12 December 2020

Metabolism of flurazepam by the small intestine

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12 December 2020

The metabolism of talampicillin in rat, dog and man.

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12 December 2020

First pass uptake of fentanyl, meperidine, and morphine in the human lung.

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12 December 2020

P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease

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12 December 2020

Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines

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12 December 2020

Pharmacogenetics of methylation: relationship to drug metabolism

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12 December 2020

Alcohol dehydrogenase mediated acetaldehyde production by Helicobacter pylori--a possible mechanism behind gastric injury

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12 December 2020

Kinetics of Acetylsalicylic Acid Disposition in Man

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12 December 2020

Purification and characterization of a new alcohol dehydrogenase from human stomach

1 reference

12 December 2020

Human cytochrome P-450 enzymes

1 reference

12 December 2020

Drug Metabolism by the Gastrointestinal Mucosa

1 reference

12 December 2020

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

1 reference

12 December 2020

Distribution of 2-naphthol sulphotransferase and its endogenous substrate adenosine 3'-phosphate 5'-phosphosulphate in human tissues

1 reference

12 December 2020

10.2165/00003088-199426020-00007

Identifiers

DOI

1 reference

PubMed ID

8162658

Dimensions Publication ID

23 September 2017

0 references

1 reference

PubMed ID

8162658