(Q40756384)

23 September 2017

The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation (English)

1 reference

23 September 2017

Kevin T Nguyen

1

1 reference

23 September 2017

Cong S Zong

2

1 reference

23 September 2017

Shailaja Uttamsingh

3

1 reference

23 September 2017

Pallavi Sachdev

4

1 reference

23 September 2017

Monica Bhanot

5

1 reference

23 September 2017

Mai-Thao Le

6

1 reference

23 September 2017

Joseph L-K Chan

7

1 reference

23 September 2017

Lu-Hai Wang

8

1 reference

23 September 2017

language of work or name

English

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publication date

17 January 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

11107-11115

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23 September 2017

13

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Characterization of ROS1 cDNA from a human glioblastoma cell line

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Mutations of Ros differentially effecting signal transduction pathways leading to cell growth versus transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Two chimeric receptors of epidermal growth factor receptor and c-Ros that differ in their transmembrane domains have opposite effects on cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Signaling by distinct classes of phosphoinositide 3-kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Rho proteins induce metastatic properties in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Rho GTPases: signaling, migration, and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Stat3 activation is required for cellular transformation by v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Constitutive activation of STAT5 by a point mutation in the SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Differential requirement for Rho family GTPases in an oncogenic insulin-like growth factor-I receptor-induced cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Cytoskeletal tumor suppressors that block oncogenic RAS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Activation of Rho is required for ligand-independent oncogenic signaling by a mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Phospholipid-binding protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108166200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108166200

1 reference

23 September 2017

1 reference