(Q40764541)

English

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription (English)

1 reference

Europe PubMed Central

23 September 2017

object named as

Yun J Kim

4

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author name string

Kimberly B Kegel

1

1 reference

Europe PubMed Central

23 September 2017

Alison R Meloni

2

1 reference

Europe PubMed Central

23 September 2017

Yong Yi

3

1 reference

Europe PubMed Central

23 September 2017

Erin Doyle

5

1 reference

Europe PubMed Central

23 September 2017

Benjamin G Cuiffo

6

1 reference

Europe PubMed Central

23 September 2017

Ellen Sapp

7

1 reference

Europe PubMed Central

23 September 2017

Yumei Wang

8

1 reference

Europe PubMed Central

23 September 2017

Zheng-Hong Qin

9

1 reference

Europe PubMed Central

23 September 2017

J Don Chen

10

1 reference

Europe PubMed Central

23 September 2017

Joseph R Nevins

11

1 reference

Europe PubMed Central

23 September 2017

Neil Aronin

12

1 reference

Europe PubMed Central

23 September 2017

Marian DiFiglia

13

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

5 December 2001

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

277

1 reference

Europe PubMed Central

23 September 2017

7466-7476

1 reference

Europe PubMed Central

23 September 2017

9

1 reference

Europe PubMed Central

23 September 2017

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Huntingtin localization in brains of normal and Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Characterization and localization of the Huntington disease gene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Huntingtin interacts with a family of WW domain proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

ZEB represses transcription through interaction with the corepressor CtBP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Nuclear targeting of mutant Huntingtin increases toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Core filaments of the nuclear matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Intranuclear localization of snRNP antigens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Structure of the small nuclear RNP particle U1: identification of the two structural protuberances with RNP-antigens A and 70K

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Activation of p53 in cervical carcinoma cells by small molecules.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Interaction of short-range repressors with Drosophila CtBP in the embryo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

High mobility of proteins in the mammalian cell nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

In vivo analysis of Cajal body movement, separation, and joining in live human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Structural determinants outside the PXDLS sequence affect the interaction of adenovirus E1A, C-terminal interacting protein and Drosophila repressors with C-terminal binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Evidence for a function of CtBP in epithelial gene regulation and anoikis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103946200

21 January 2018

Identifiers

10.1074/JBC.M103946200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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