(Q40766529)

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The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: studies using chimeric human and fly receptors

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Europe PubMed Central

PubMed publication ID

23 September 2017

The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: studies using chimeric human and fly receptors (English)

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Europe PubMed Central

PubMed publication ID

23 September 2017

transmembrane protein

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3

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Brian Kobilka

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Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Shinya Nishi

1

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Europe PubMed Central

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23 September 2017

Koji Nakabayashi

2

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Europe PubMed Central

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23 September 2017

Aaron J W Hsueh

4

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23 September 2017

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publication date

26 November 2001

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23 September 2017

Journal of Biological Chemistry

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23 September 2017

277

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PubMed publication ID

23 September 2017

6

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Europe PubMed Central

PubMed publication ID

23 September 2017

3958-3964

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Molecular mechanism of LH/CG receptor activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109617200

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The luteinizing hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109617200

21 January 2018

TSH receptor and disease

1 reference

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Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

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The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7

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Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster

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The nematode leucine-rich repeat-containing, G protein-coupled receptor (LGR) protein homologous to vertebrate gonadotropin and thyrotropin receptors is constitutively active in mammalian cells

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Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals

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A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction

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Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

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G protein-coupled receptor structure and function: the impact of disease-causing mutations

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Genetic heterogeneity of constitutively activating mutations of the human luteinizing hormone receptor in familial male-limited precocious puberty.

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Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281-->isoleucine) in the extracellular domain of the thyrotropin receptor

1 reference

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21 January 2018

Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region

1 reference

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21 January 2018

The role of the hinge region of the luteinizing hormone receptor in hormone interaction and signal generation

1 reference

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Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function

1 reference

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21 January 2018

Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop

1 reference

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21 January 2018

Expression of human luteinizing hormone (LH) receptor: interaction with LH and chorionic gonadotropin from human but not equine, rat, and ovine species

1 reference

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21 January 2018

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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Hormone interactions to Leu-rich repeats in the gonadotropin receptors. I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor

1 reference

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21 January 2018

Hormone interactions to Leu-rich repeats in the gonadotropin receptors. II. Analysis of Leu-rich repeat 4 of human luteinizing hormone/chorionic gonadotropin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109617200

21 January 2018

Mutations of the second extracellular loop of the human lutropin receptor emphasize the importance of receptor activation and de-emphasize the importance of receptor phosphorylation in agonist-induced internalization

1 reference

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21 January 2018

Lys583 in the third extracellular loop of the lutropin/choriogonadotropin receptor is critical for signaling

1 reference

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21 January 2018

Exoloop 3 of the luteinizing hormone/choriogonadotropin receptor. Lys583 is essential and irreplaceable for human choriogonadotropin (hCG)-dependent receptor activation but not for high affinity hCG binding

1 reference

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21 January 2018

Co-expression of defective luteinizing hormone receptor fragments partially reconstitutes ligand-induced signal generation

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21 January 2018

Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome

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Vasoactive intestinal peptide: a novel stimulator of steroidogenesis by cultured rat granulosa cells

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Enzymatic Radioiodination of Gonadotropins

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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

1 reference

11 October 2022

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Modulation of high affinity hormone binding. Human choriogonadotropin binding to the exodomain of the receptor is influenced by exoloop 2 of the receptor

1 reference

11 October 2022

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The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design

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Hormone interactions to Leu-rich repeats in the gonadotropin receptors. III. Photoaffinity labeling of human chorionic gonadotropin with receptor Leu-rich repeat 4 peptide

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Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain

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Identification of hormone-binding regions of the luteinizing hormone/human chorionic gonadotropin receptor using synthetic peptides

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Characterization of two fly LGR (leucine-rich repeat-containing, G protein-coupled receptor) proteins homologous to vertebrate glycoprotein hormone receptors: constitutive activation of wild-type fly LGR1 but not LGR2 in transfected mammalian cells

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11 October 2022

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Identifiers

10.1074/JBC.M109617200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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