(Q40769630)

23 September 2017

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function (English)

1 reference

23 September 2017

4

1 reference

23 September 2017

William A Cliby

1

1 reference

23 September 2017

Kriste A Lewis

series ordinal

2

1 reference

23 September 2017

Kia K Lilly

series ordinal

3

1 reference

23 September 2017

language of work or name

English

0 references

publication date

7 November 2001

1 reference

Journal of Biological Chemistry

23 September 2017

1 reference

23 September 2017

277

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23 September 2017

1599-1606

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23 September 2017

2

1 reference

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Control of cell cycle arrest by the Mec1sc/Rad3sp DNA structure checkpoint pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

The G2-phase DNA-damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Replication checkpoint: preventing mitotic catastrophe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Regulation of chromosome replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Checkpoints controlling mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Cell-cycle checkpoint kinases: checking in on the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Topoisomerase I-mediated DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Tumor cell death induced by topoisomerase-targeting drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

The S-phase cytotoxicity of camptothecin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Exposure to camptothecin breaks leading and lagging strand simian virus 40 DNA replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Comparison of paclitaxel-, 5-fluoro-2'-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Targeting double-strand breaks to replicating DNA identifies a subpathway of DSB repair that is defective in ataxia-telangiectasia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Roadblocks and detours during DNA replication: mechanisms of mutagenesis in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Purification and characterization of human DNA damage checkpoint Rad complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

The ATM protein is required for sustained activation of NF-kappaB following DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Cell death induced by topoisomerase-targeted drugs: more questions than answers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells: elevated dTTP pools and enhanced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106287200

21 January 2018

Identifiers

DOI

10.1074/JBC.M106287200

1 reference

release_mu3gzxsr55d27lp2zkv5yzkxsq

23 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mu3gzxsr55d27lp2zkv5yzkxsq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference