(Q40815505)

24 September 2017

title

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity (English)

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24 September 2017

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1

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24 September 2017

4

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24 September 2017

5

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24 September 2017

Harding A

2

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24 September 2017

Yan J

series ordinal

3

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24 September 2017

Hancock JF

series ordinal

6

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24 September 2017

publication date

1 April 2001

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24 September 2017

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24 September 2017

volume

3

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24 September 2017

issue

4

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24 September 2017

page(s)

368-375

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

24 September 2017

cites work

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7 January 2021

The murine N-ras gene is not essential for growth and development

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7 January 2021

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

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7 January 2021

Increasing complexity of Ras signaling.

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7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

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7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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7 January 2021

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

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7 January 2021

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

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7 January 2021

Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

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7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

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7 January 2021

Lipid domain structure of the plasma membrane revealed by patching of membrane components

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7 January 2021

Functionally different GPI proteins are organized in different domains on the neuronal surface

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7 January 2021

Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

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7 January 2021

Reduction of caveolin and caveolae in oncogenically transformed cells

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7 January 2021

Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.

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7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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7 January 2021

Stimulation of p21 ras upon T-cell activation

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7 January 2021

Stimulation of nucleotide exchange on Ras- and Rho-related proteins by small GTP-binding protein GDP dissociation stimulator

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7 January 2021

The complexity of Raf-1 regulation

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7 January 2021

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

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7 January 2021

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo

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7 January 2021

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

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7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

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7 January 2021

Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies.

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7 January 2021

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

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7 January 2021

Lipid-dependent Targeting of G Proteins into Rafts

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7 January 2021

Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells

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7 January 2021

Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy

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7 January 2021

Regulated migration of epidermal growth factor receptor from caveolae

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7 January 2021

Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans

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7 January 2021

Identifiers

DOI

10.1038/35070050

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Dimensions Publication ID

24 September 2017

1025750222

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