(Q40816316)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279124%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine (English)

1 reference

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6 November 2019

0 references

8

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6 November 2019

author name string

D Curman

1

1 reference

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6 November 2019

B Cinel

2

1 reference

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6 November 2019

D E Williams

3

1 reference

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6 November 2019

N Rundle

4

1 reference

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6 November 2019

W D Block

5

1 reference

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6 November 2019

A A Goodarzi

6

1 reference

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6 November 2019

J R Hutchins

7

1 reference

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6 November 2019

B B Zhou

9

1 reference

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6 November 2019

S P Lees-Miller

10

1 reference

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6 November 2019

R J Andersen

11

1 reference

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6 November 2019

M Roberge

12

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6 November 2019

language of work or name

English

0 references

publication date

7 March 2001

1 reference

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Journal of Biological Chemistry

6 November 2019

published in

1 reference

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6 November 2019

volume

276

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6 November 2019

page(s)

17914-17919

1 reference

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6 November 2019

issue

21

1 reference

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Sensing and responding to DNA damage.

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Checkpoints controlling mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Checkpoint pathways come of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Effects of caffeine on radiation-induced phenomena associated with cell-cycle traverse of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

The effect of caffeine on X-ray-induced mitotic delay in normal human and ataxia-telangiectasia fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

2-Aminopurine overrides multiple cell cycle checkpoints in BHK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

The topoisomerase II inhibitor VM-26 induces marked changes in histone H1 kinase activity, histones H1 and H3 phosphorylation, and chromosome condensation in G2 phase and mitotic BHK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100728200

21 January 2018

Identifiers

DOI

10.1074/JBC.M100728200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279124%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference