(Q40857239)

24 September 2017

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title

TNF-alpha and insulin resistance: summary and future prospects (English)

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24 September 2017

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Peraldi P

1

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PubMed ID

9609126

24 September 2017

Spiegelman B

series ordinal

2

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24 September 2017

1 May 1998

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Molecular and Cellular Biochemistry

24 September 2017

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24 September 2017

182

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24 September 2017

169-175

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24 September 2017

1-2

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https://scigraph.springernature.com/pub.10.1023/a:1006865715292

24 September 2017

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cites work

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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Phosphorylation of Raf by ceramide-activated protein kinase

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A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF

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Ceramide stimulates a cytosolic protein phosphatase

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The insulin signaling system

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

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12 December 2020

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase

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12 December 2020

Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells

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12 December 2020

Transcriptional repression of the C/EBP-alpha and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulations is coordinate and independent of protein synthesis

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12 December 2020

Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level

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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

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12 December 2020

The pathophysiology of tumor necrosis factors

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12 December 2020

Tumor necrosis factor, other cytokines and disease

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I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

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12 December 2020

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha

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12 December 2020

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

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12 December 2020

Processing of tumour necrosis factor-α precursor by metalloproteinases

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12 December 2020

Insulin resistance in patients with colorectal cancer.

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12 December 2020

A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia

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12 December 2020

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

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12 December 2020

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

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12 December 2020

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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12 December 2020

The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

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12 December 2020

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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12 December 2020

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

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12 December 2020

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

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12 December 2020

Two tumour necrosis factor receptors: structure and function.

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12 December 2020

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

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12 December 2020

How do tumor necrosis factor receptors work?

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12 December 2020

The two different receptors for tumor necrosis factor mediate distinct cellular responses

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12 December 2020

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

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12 December 2020

The metabolic effects of tumor necrosis factor and other cytokines

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12 December 2020

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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12 December 2020

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

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12 December 2020

FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase

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12 December 2020

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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12 December 2020

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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12 December 2020

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

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12 December 2020

Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output

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12 December 2020

Purification and partial characterization of the phosphatidylinositol 4-phosphate kinase from rat brain

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12 December 2020

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

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12 December 2020

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

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12 December 2020

Cachectin/TNF production in experimental burns and Pseudomonas infection

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12 December 2020

Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.

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12 December 2020

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

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12 December 2020

Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling

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12 December 2020

Mechanisms of fatty acid-induced inhibition of glucose uptake

1 reference

12 December 2020

Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase

1 reference

12 December 2020

Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance.

1 reference

12 December 2020

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1006865715292

1 reference

PubMed ID

9609126

Dimensions Publication ID

24 September 2017

0 references

1 reference

PubMed ID

9609126