(Q40872114)

24 September 2017

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title

Signal transduction pathways and their relevance in human astrocytomas (English)

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24 September 2017

Feldkamp MM

1

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24 September 2017

Lau N

series ordinal

2

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24 September 2017

Guha A

series ordinal

3

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24 September 2017

language of work or name

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1 December 1997

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Journal of Neuro-Oncology

24 September 2017

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24 September 2017

35

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24 September 2017

223-248

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24 September 2017

3

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https://scigraph.springernature.com/pub.10.1023/a:1005800114912

24 September 2017

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cites work

Expression pattern of alpha-protein kinase C in human astrocytomas indicates a role in malignant progression

1 reference

12 December 2020

Dynamic fatty acylation of p21N-ras

1 reference

12 December 2020

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1 reference

12 December 2020

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct

1 reference

12 December 2020

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

12 December 2020

Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

1 reference

12 December 2020

Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells

1 reference

12 December 2020

Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6).

1 reference

12 December 2020

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein

1 reference

12 December 2020

Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C

1 reference

12 December 2020

Functional analysis of a growth factor-responsive transcription factor complex

1 reference

12 December 2020

Pleckstrin domain homology

1 reference

12 December 2020

Pathways of Ras function: connections to the actin cytoskeleton.

1 reference

12 December 2020

Prenyl proteins in eukaryotic cells: a new type of membrane anchor

1 reference

12 December 2020

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

1 reference

12 December 2020

Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated

1 reference

12 December 2020

The signal-dependent coactivator CBP is a nuclear target for pp90RSK

1 reference

12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

12 December 2020

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes

1 reference

12 December 2020

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

12 December 2020

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

12 December 2020

Critical role of Rho in cell transformation by oncogenic Ras.

1 reference

12 December 2020

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

1 reference

12 December 2020

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

1 reference

12 December 2020

A negative feedback loop attenuates EGF-induced morphological changes

1 reference

12 December 2020

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

1 reference

12 December 2020

Epidermal growth factor increases protein and messenger RNA expression levels of Ras GTPase activating protein

1 reference

12 December 2020

Mechanisms of glioma invasion: role of matrix-metalloproteinases

1 reference

12 December 2020

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1 reference

12 December 2020

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

1 reference

12 December 2020

Protein modules and signalling networks

1 reference

12 December 2020

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1 reference

12 December 2020

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

1 reference

12 December 2020

Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain

1 reference

12 December 2020

Genistein, a specific inhibitor of tyrosine-specific protein kinases

1 reference

12 December 2020

Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B956

1 reference

12 December 2020

Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen

1 reference

12 December 2020

Activation of the epidermal growth factor receptor tyrosine protein kinase in the absence of receptor oligomerization

1 reference

12 December 2020

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

12 December 2020

Differential regulation of rasGAP and neurofibromatosis gene product activities

1 reference

12 December 2020

Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

1 reference

12 December 2020

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

12 December 2020

Effect of tyrphostin on cell growth and tyrosine kinase activity of epidermal growth factor receptor in human gliomas

1 reference

12 December 2020

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

1 reference

12 December 2020

Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases

1 reference

12 December 2020

Effect of tamoxifen on DNA synthesis and proliferation of human malignant glioma lines in vitro.

1 reference

12 December 2020

Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea

1 reference

12 December 2020

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1 reference

12 December 2020

Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis

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12 December 2020

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1 reference

12 December 2020

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

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12 December 2020

Regulation of signal transduction and signal diversity by receptor oligomerization

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12 December 2020

Protein kinase C alpha activates RAF-1 by direct phosphorylation

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12 December 2020

Identification of the sites of interaction between c-Raf-1 and Ras-GTP

1 reference

12 December 2020

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

12 December 2020

Expression of an altered epidermal growth factor receptor by human glioblastoma cells

1 reference

12 December 2020

Activation of the MAP kinase pathway by the protein kinase raf

1 reference

12 December 2020

Inhibition of cell growth by lovastatin is independent of ras function

1 reference

12 December 2020

Expression of neu/c-erbB-2 in human brain tumors.

1 reference

12 December 2020

Two types of RAS mutants that dominantly interfere with activators of RAS.

1 reference

12 December 2020

Molecular localization of the transforming and secretory properties of PDGF A and PDGF B.

1 reference

12 December 2020

cDNA sequence and genomic structure of EV12B, a gene lying within an intron of the neurofibromatosis type 1 gene

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12 December 2020

Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor

1 reference

12 December 2020

Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling

1 reference

12 December 2020

Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro

1 reference

12 December 2020

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys

1 reference

12 December 2020

Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against

1 reference

12 December 2020

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

12 December 2020

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

12 December 2020

Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains

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12 December 2020

Tyrosine kinase inhibition: an approach to drug development

1 reference

12 December 2020

Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I

1 reference

12 December 2020

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines

1 reference

12 December 2020

Growth factor signaling by receptor tyrosine kinases

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12 December 2020

RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

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12 December 2020

Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells

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12 December 2020

Oncogenes and signal transduction

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12 December 2020

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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12 December 2020

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

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12 December 2020

Gene amplification in human gliomas

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12 December 2020

Activation of Raf as a result of recruitment to the plasma membrane

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12 December 2020

Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta

1 reference

12 December 2020

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

12 December 2020

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

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12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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12 December 2020

Transformational and altered signal transduction by a naturally occurring mutant EGF receptor

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12 December 2020

Antisense epidermal growth factor receptor transfection impairs the proliferative ability of human rhabdomyosarcoma cells

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12 December 2020

p120 Ras GTPase-activating protein interacts with Ras-GTP through specific conserved residues

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12 December 2020

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

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12 December 2020

Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins

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12 December 2020

Regulation of protein kinases activity by quercetin in Ehrlich ascites tumor cells

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12 December 2020

Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors

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12 December 2020

Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction

1 reference

12 December 2020

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

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12 December 2020

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

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12 December 2020

Resistance of a variant ras-transformed cell line to phenotypic reversion by farnesyl transferase inhibitors.

1 reference

12 December 2020

SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways

1 reference

12 December 2020

Characterization and differential distribution of the three major human protein kinase C isozymes (PKC alpha, PKC beta, and PKC gamma) of the central nervous system in normal and Alzheimer's disease brains.

1 reference

12 December 2020

Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop.

1 reference

12 December 2020

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1 reference

12 December 2020

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

1 reference

12 December 2020

The coordinated action of protein tyrosine phosphatases and kinases in cell signaling

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12 December 2020

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

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12 December 2020

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

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12 December 2020

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

1 reference

12 December 2020

Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

1 reference

12 December 2020

Growth factor stimulation of phospholipase C-gamma 1 activity. Comparative properties of control and activated enzymes

1 reference

12 December 2020

Immunocytochemical localization of the alpha subspecies of protein kinase C in rat brain

1 reference

12 December 2020

A tiger behind many doors: multiple genetic pathways to malignant glioma

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12 December 2020

Role of protein kinase C in glial cell proliferation

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12 December 2020

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12 December 2020

Induction of proto-oncogene JUN/AP-1 by serum and TPA.

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12 December 2020

Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors

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12 December 2020

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

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12 December 2020

4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase

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12 December 2020

Sequence dependence of protein isoprenylation

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12 December 2020

Signal transduction. How receptors turn Ras on.

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12 December 2020

The 3Rs of life: Ras, Raf and growth regulation

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12 December 2020

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

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12 December 2020

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin

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12 December 2020

Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

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12 December 2020

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin

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12 December 2020

Two classes of PDGF receptor recognize different isoforms of PDGF

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12 December 2020

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors

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12 December 2020

Constitutive phosphorylation of the epidermal growth factor receptor blocks mitogenic signal transduction.

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12 December 2020

Dimerization of cell surface receptors in signal transduction

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12 December 2020

Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells

1 reference

12 December 2020

Dominant-negative mutants of a platelet-derived growth factor gene

1 reference

12 December 2020

Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes

1 reference

12 December 2020

Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product

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12 December 2020

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

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12 December 2020

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

1 reference

12 December 2020

Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors

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12 December 2020

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

1 reference

12 December 2020

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1 reference

12 December 2020

Expression of epidermal growth factor receptors in human brain tumors

1 reference

12 December 2020

Platelet-derived growth factor: a general review with emphasis on astrocytomas

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12 December 2020

Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

1 reference

12 December 2020

Loss of neurofibromin in adrenal gland tumors from patients with neurofibromatosis type I

1 reference

12 December 2020

The identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon, and zeta

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12 December 2020

Protein prenylation: a mediator of protein-protein interactions

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12 December 2020

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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12 December 2020

A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

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12 December 2020

Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin A methyl ester in cultured A431 cells

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12 December 2020

Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism

1 reference

12 December 2020

Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction

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12 December 2020

PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

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12 December 2020

Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins

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12 December 2020

Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor

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12 December 2020

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12 December 2020

An essential role for Rac in Ras transformation

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12 December 2020

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

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12 December 2020

Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways.

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12 December 2020

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

1 reference

12 December 2020

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

1 reference

12 December 2020

Protein-tyrosine kinases, oncogenes, and cancer

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12 December 2020

ras oncogenes in human cancer: a review

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12 December 2020

SH2 domains recognize specific phosphopeptide sequences

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12 December 2020

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

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12 December 2020

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

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12 December 2020

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

12 December 2020

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1 reference

12 December 2020

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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12 December 2020

Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

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12 December 2020

Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype

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12 December 2020

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

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12 December 2020

Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifen

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12 December 2020

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

12 December 2020

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class

1 reference

12 December 2020

The treatment of intracranial malignant gliomas using orally administered tamoxifen therapy: preliminary results in a series of "failed" patients

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12 December 2020

The phorbol ester receptor: a phospholipid-regulated protein kinase

1 reference

12 December 2020

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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12 December 2020

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

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12 December 2020

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB.

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12 December 2020

Raf-1 activates MAP kinase-kinase

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12 December 2020

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

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12 December 2020

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

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12 December 2020

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

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12 December 2020

In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors

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12 December 2020

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

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12 December 2020

Complexities of the protein kinase C pathway

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12 December 2020

Accelerated degradation of 160 kDa epidermal growth factor (EGF) receptor precursor by the tyrosine kinase inhibitor herbimycin A in the endoplasmic reticulum of A431 human epidermoid carcinoma cells

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12 December 2020

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

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12 December 2020

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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12 December 2020

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

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12 December 2020

A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions

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12 December 2020

AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE.

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12 December 2020

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

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12 December 2020

Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.

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12 December 2020

SH2 and SH3 domains: from structure to function

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12 December 2020

Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas

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12 December 2020

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

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12 December 2020

Morphologic responses to a murine erythroblastosis virus.

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12 December 2020

The neu oncogene encodes an epidermal growth factor receptor-related protein

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12 December 2020

Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains

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12 December 2020

The neurofibromatosis type 1 gene encodes a protein related to GAP

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12 December 2020

Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

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12 December 2020

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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12 December 2020

EGF receptor in neoplasia and metastasis

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12 December 2020

Acute presentation of a neurogenic sarcoma in a patient with neurofibromatosis type 1: a pathological and molecular explanation. Case report

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12 December 2020

Proliferation of human malignant astrocytomas is dependent on Ras activation.

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12 December 2020

Lovastatin selectively inhibits ras activation of the 12-O-tetradecanoylphorbol-13-acetate response element in mammalian cells

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12 December 2020

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

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12 December 2020

Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.

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12 December 2020

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

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12 December 2020

Requirement for c-ras proteins during viral oncogene transformation

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12 December 2020

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

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12 December 2020

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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12 December 2020

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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12 December 2020

Protein kinase C isoforms in human glioblastoma cells

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12 December 2020

Protein kinase C-activating tumor promoters enhance the differentiation of astrocytes in aggregating fetal brain cell cultures.

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12 December 2020

Regulatory mechanisms for ras proteins

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12 December 2020

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

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12 December 2020

A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction

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12 December 2020

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

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12 December 2020

A putative modular domain present in diverse signaling proteins

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12 December 2020

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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12 December 2020

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

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12 December 2020

Ras-GTP levels are elevated in human NF1 peripheral nerve tumors

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12 December 2020

Identification of NF1 mutations in both alleles of a dermal neurofibroma

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12 December 2020

Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells.

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12 December 2020

Ras signaling and NF1.

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12 December 2020

Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13→q22 region of chromosome 7

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12 December 2020

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

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12 December 2020

CaLB: a 43 amino acid calcium-dependent membrane/phospholipid binding domain in p120 Ras GTPase-activating protein.

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12 December 2020

Benign neurofibromas in type 1 neurofibromatosis (NF1) show somatic deletions of the NF1 gene

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12 December 2020

Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus onc gene

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12 December 2020

Src homology region 2 domains direct protein-protein interactions in signal transduction

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12 December 2020

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

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12 December 2020

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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12 December 2020

Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification

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12 December 2020

Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3

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12 December 2020

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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12 December 2020

MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes.

1 reference

12 December 2020

Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts.

1 reference

12 December 2020

Reversal of transformed phenotypes by herbimycin A in src oncogene expressed rat fibroblasts.

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12 December 2020

Unfarnesylated transforming Ras mutant inhibits the Ras-signaling pathway by forming a stable Ras.Raf complex in the cytosol

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12 December 2020

Expression of growth factor receptors in human brain tumours

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12 December 2020

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12 December 2020

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

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12 December 2020

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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12 December 2020

Identifiers

DOI

10.1023/A:1005800114912

1 reference

Dimensions Publication ID

24 September 2017

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