(Q40875121)

24 September 2017

Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells (English)

1 reference

24 September 2017

1 reference

Valentinis B

1

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24 September 2017

Navarro M

2

1 reference

24 September 2017

Zanocco-Marani T

3

1 reference

24 September 2017

Edmonds P

4

1 reference

24 September 2017

McCormick J

5

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24 September 2017

Morrione A

6

1 reference

24 September 2017

Sacchi A

7

1 reference

24 September 2017

Romano G

8

1 reference

24 September 2017

Reiss K

9

1 reference

24 September 2017

Baserga R

10

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24 September 2017

language of work or name

English

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publication date

1 August 2000

1 reference

Journal of Biological Chemistry

24 September 2017

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24 September 2017

275

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24 September 2017

25451-25459

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24 September 2017

33

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Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Co-operation of simian virus 40 T antigen and insulin receptor substrate-1 in protection from apoptosis induced by interleukin-3 withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Drosophila S6 kinase: a regulator of cell size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Ribosomal S6 kinase signaling and the control of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Okadaic acid: a new probe for the study of cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Mycoplasmal infections prevent apoptosis and induce malignant transformation of interleukin-3-dependent 32D hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Insulin signal transduction through protein kinase cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Role of binding proteins to IRS-1 in insulin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Activation of the ribosomal DNA promoter in cells exposed to insulinlike growth factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Prolonged vs transient roles for early cell cycle signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

Multiple Signals Mediate Proliferation, Differentiation, and Survival from the Granulocyte Colony-stimulating Factor Receptor in Myeloid 32D Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

p70s6k function is essential for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002271200

21 January 2018

Identifiers

DOI

10.1074/JBC.M002271200

1 reference

24 September 2017

1 reference