(Q40907787)

24 September 2017

JNK2 and IKKbeta are required for activating the innate response to viral infection (English)

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24 September 2017

B Williams

7

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author name string

W M Chu

1

1 reference

24 September 2017

D Ostertag

2

1 reference

24 September 2017

Z W Li

3

1 reference

24 September 2017

L Chang

4

1 reference

24 September 2017

Y Chen

5

1 reference

24 September 2017

Y Hu

6

1 reference

24 September 2017

J Perrault

8

1 reference

24 September 2017

M Karin

9

1 reference

24 September 2017

language of work or name

English

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publication date

1 December 1999

1 reference

24 September 2017

1 reference

24 September 2017

11

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24 September 2017

721-731

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24 September 2017

6

1 reference

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

NF-kappaB activation Is delayed in mouse L929 cells infected with interferon suppressing, but not inducing, vesicular stomatitis virus strains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The double-stranded RNA-dependent protein kinase PKR: structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Phylogenetic perspectives in innate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Signaling by the cytokine receptor superfamily: JAKs and STATs.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The war against the interferon-induced dsRNA-activated protein kinase: can viruses win?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Different pathways mediate virus inducibility of the human IFN-alpha 1 and IFN-beta genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Signal transduction through NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Innate immunity: the virtues of a nonclonal system of recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Functional role of type I and type II interferons in antiviral defense

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Human cytomegalovirus induces IL-6 and TNF alpha from macrophages and microglial cells: possible role in neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Critical role of a common transcription factor, IRF-1, in the regulation of IFN-beta and IFN-inducible genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Regulation of type I interferon gene expression by interferon regulatory factor-3.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980146-6

7 January 2021

10.1016/S1074-7613(00)80146-6

Identifiers

DOI

1 reference

24 September 2017

1 reference