(Q40923146)

24 September 2017

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title

Amlodipine. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease (English)

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24 September 2017

cardiovascular disease

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M Haria

1

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PubMed ID

8521773

24 September 2017

A J Wagstaff

series ordinal

2

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24 September 2017

1 September 1995

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24 September 2017

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24 September 2017

50

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24 September 2017

560-586

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24 September 2017

3

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https://scigraph.springernature.com/pub.10.2165/00003495-199550030-00009

24 September 2017

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1 reference

12 December 2020

The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily

1 reference

12 December 2020

Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide

1 reference

12 December 2020

Open comparative study to assess the efficacy and safety of two calcium antagonists, amlodipine and diltiazem, in the treatment of symptomatic myocardial ischaemia

1 reference

12 December 2020

Epidemiology of hypertension

1 reference

12 December 2020

Improvement of insulin sensitivity for glucose metabolism with the long-acting Ca-channel blocker amlodipine in essential hypertensive subjects

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12 December 2020

Parkinsonism induced by amlodipine

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12 December 2020

Long-term efficacy of amlodipine in patients with severe coronary artery disease

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12 December 2020

Amlodipine in elderly hypertensive patients: pharmacokinetics and pharmacodynamics

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12 December 2020

Efficacy and safety of amlodipine in hypertensive patients with renal dysfunction

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12 December 2020

Biotransformation of amlodipine. Identification and synthesis of metabolites found in rat, dog and human urine/confirmation of structures by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry

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12 December 2020

Block of heart calcium channels by amlodipine: influence of drug charge on blocking activity.

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12 December 2020

Clinical pharmacokinetics of amlodipine

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12 December 2020

Pathophysiological mechanisms underlying the adverse effects of calcium channel-blocking drugs in patients with chronic heart failure

1 reference

12 December 2020

Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition

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12 December 2020

Pharmacokinetics of calcium antagonists

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12 December 2020

The effects of the calcium antagonist amlodipine on blood pressure and platelet aggregation in hypertensive patients

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12 December 2020

Pharmacokinetics of amlodipine in renal impairment

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12 December 2020

A multicentre study of the safety and efficacy of amlodipine in mild to moderate hypertension

1 reference

12 December 2020

Metabolism and kinetics of amlodipine in man.

1 reference

12 December 2020

Amlodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiovascular disease

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12 December 2020

Amlodipine: a once daily calcium antagonist

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12 December 2020

The calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hypertensive men.

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12 December 2020

Clinical pharmacokinetics of calcium antagonists. An update

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12 December 2020

Amlodipine versus atenolol in essential hypertension

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12 December 2020

Haemodynamic and electrophysiological effects of amlodipine, a new long-acting calcium antagonist

1 reference

12 December 2020

Calcium antagonists for treatment of diabetes-associated hypertension. Metabolic and renal effects of amlodipine

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12 December 2020

Cellular electrophysiology of amlodipine: probing the cardiac L-type calcium channel

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12 December 2020

Blood pressure and coronary heart disease

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12 December 2020

Amlodipine with enalapril therapy in moderate-severe essential hypertension

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12 December 2020

Efficacy of amlodipine besilate therapy for variant angina: evaluation by 24-hour Holter monitoring

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12 December 2020

Limits of lipid-lowering therapy: the benefits of amlodipine as an anti-atherosclerotic agent.

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12 December 2020

Long-term open evaluation of amlodipine vs hydrochlorothiazide in patients with essential hypertension

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12 December 2020

An 8-week double-blind study of amlodipine and diltiazem in patients with stable exertional angina pectoris

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12 December 2020

Dermatologic cross-sensitivity between diltiazem and amlodipine.

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12 December 2020

Cardioprotective effects of amlodipine on ischemia and reperfusion in two experimental models

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12 December 2020

The antiatherogenic effects of amlodipine: promise of preclinical data

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12 December 2020

Double-blind evaluation of the dose-response relationship of amlodipine in essential hypertension

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12 December 2020

Effects of different antihypertensive drugs on plasma fibrinogen in hypertensive patients

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12 December 2020

The use of self-measured blood pressure determinations in assessing dynamics of drug compliance in a study with amlodipine once a day, morning versus evening.

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12 December 2020

Cardiovascular structural changes and calcium antagonist therapy in patients with hypertension

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12 December 2020

Amlodipine pharmacokinetics in healthy volunteers

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12 December 2020

Coronary vascular reactivity and calcium antagonist therapy in patients with angina

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12 December 2020

Protective effect of pretreatment with verapamil, nifedipine and propranolol on mitochondrial function in the ischemic and reperfused myocardium

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12 December 2020

Characteristics of participants at baseline in the Treatment of Mild Hypertension Study (TOMHS)

1 reference

12 December 2020

Amlodipine: a once-daily calcium antagonist in the treatment of angina pectoris--a parallel dose-response, placebo-controlled study. The Amlodipine Study Group

1 reference

12 December 2020

Patient compliance and therapeutic coverage: comparison of amlodipine and slow release nifedipine in the treatment of hypertension. The Belgian Collaborative Study Group

1 reference

12 December 2020

Photodistributed nifedipine-induced facial telangiectasia

1 reference

12 December 2020

Double-blind comparison of amlodipine and nifedipine retard in the treatment of mild to moderate hypertension

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12 December 2020

Emerging options in the management of myocardial ischemia

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12 December 2020

Effects of amlodipine on platelet aggregation and blood pressure in patients with essential hypertension

1 reference

12 December 2020

Amlodipine in patients with angina uncontrolled by atenolol. A double blind placebo controlled cross over trial

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12 December 2020

A haemodynamic dose finding study with a new slow-calcium channel blocker (amlodipine) in coronary artery disease

1 reference

12 December 2020

[Non-thrombopenic purpura induced by amlodipine]

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12 December 2020

Absence of hemodynamic deterioration in the presence of amlodipine following experimental myocardial infarction

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12 December 2020

Intra-arterial monitoring of the antihypertensive effects of once-daily amlodipine

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12 December 2020

Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension

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12 December 2020

Amlodipine therapy corrects renal abnormalities encountered in the hypertensive state.

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12 December 2020

Calcium antagonists for congestive heart failure: evolving concepts in bridge building

1 reference

12 December 2020

The circadian rhythm of angina pectoris. Amlodipine Angina Studies Group

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12 December 2020

Pharmacodynamic modeling of the antihypertensive response to amlodipine

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12 December 2020

Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard.

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12 December 2020

Vascular injury: Mechanisms and manifestations

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12 December 2020

Cardioprotective effects of amlodipine in the ischemic-reperfused heart.

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12 December 2020

Amlodipine, a long-acting calcium antagonist drug reduces ischemia-induced ventricular conduction delay in pig hearts

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12 December 2020

The pharmacokinetic profile of amlodipine

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12 December 2020

Acute, chronic and postwithdrawal antihypertensive and renal effects of amlodipine in hypertensive patients

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12 December 2020

A dose-response study of amlodipine in mild to moderate hypertension

1 reference

12 December 2020

Antihypertensive effect of amlodipine and lack of interference with cyclosporine metabolism in renal transplant recipients.

1 reference

12 December 2020

Comparative evaluation of the antihypertensive efficacy of once-daily amlodipine versus nitrendipine with 24-hour ambulatory blood pressure monitoring in essential hypertension

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12 December 2020

Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS)

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12 December 2020

Combination therapy with amlodipine and captopril for resistant systemic hypertension.

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12 December 2020

Evaluation and quality-of-life assessment of amlodipine and enalapril in patients with hypertension.

1 reference

12 December 2020

Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group

1 reference

12 December 2020

A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results.

1 reference

12 December 2020

A four-week double-blind, placebo-controlled, parallel dose-response study of amlodipine in patients with stable exertional angina pectoris

1 reference

12 December 2020

A double-blind dose-response study of amlodipine in patients with stable angina pectoris

1 reference

12 December 2020

The metabolism and pharmacokinetics of amlodipine in humans and animals

1 reference

12 December 2020

Amlodipine once a day in stable angina: double-blind crossover comparison with placebo

1 reference

12 December 2020

Gynaecomastia and amlodipine

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12 December 2020

1 reference

12 December 2020

The effect of amlodipine on ambulatory blood pressure in hypertensive patients

1 reference

12 December 2020

Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.

1 reference

12 December 2020

Amlodipine pretreatment and the ischemic heart

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12 December 2020

Amlodipine reduces transient myocardial ischemia in patients with coronary artery disease: double-blind Circadian Anti-Ischemia Program in Europe (CAPE Trial).

1 reference

12 December 2020

Long-term double-blind evaluation of amlodipine and nadolol in patients with stable exertional angina pectoris. The Investigators of Study 152

1 reference

12 December 2020

Amlodipine compared to nitrendipine in hypertensive patients: the effects on toleration in relationship to the onset of action

1 reference

12 December 2020

Blood pressure, stroke, and coronary heart disease

1 reference

12 December 2020

Calcium antagonists for congestive heart failure: is it really one bridge too far to cross?

1 reference

12 December 2020

Pharmacokinetic interaction study between benazepril and amlodipine in healthy subjects

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12 December 2020

Effects of amlodipine on steady-state digoxin concentrations and renal digoxin clearance.

1 reference

12 December 2020

Gingival sequestration of amlodipine and amlodipine-induced gingival overgrowth

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12 December 2020

Effects of amlodipine versus diltiazem on morning peak in myocardial ischemic activity in angina pectoris

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12 December 2020

Antihypertensive therapy--efficacy and quality of life

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12 December 2020

Lack of effect of long-term amlodipine on insulin sensitivity and plasma insulin in obese patients with essential hypertension.

1 reference

12 December 2020

Randomized placebo-controlled trial of amlodipine in vasospastic angina. Amlodipine Study 160 Group.

1 reference

12 December 2020

Haemodynamic comparison of amlodipine and atenolol in essential hypertension using the quantascope

1 reference

12 December 2020

Circadian variation and triggers of onset of acute cardiovascular disease

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12 December 2020

Absorption of amlodipine unaffected by food. Solid dose equivalent to solution dose.

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12 December 2020

Pharmacokinetics and safety of single oral doses of amlodipine in patients with and without hepatic impairment: an open study

1 reference

12 December 2020

Gingival enlargement in a patient medicated with amlodipine

1 reference

12 December 2020

The treatment of mild hypertension study. A randomized, placebo-controlled trial of a nutritional-hygienic regimen along with various drug monotherapies. The Treatment of Mild Hypertension Research Group

1 reference

12 December 2020

Effect of amlodipine, atenolol and their combination on myocardial ischemia during treadmill exercise and ambulatory monitoring. Canadian Amlodipine/Atenolol in Silent Ischemia Study (CASIS) Investigators

1 reference

12 December 2020

Comparison of the effects of amlodipine and captopril on clinic and ambulatory blood pressure

1 reference

12 December 2020

[Monotherapy of mild to moderate hypertension. Double-blind comparative study: amlodipine versus enalapril]

1 reference

12 December 2020

The safety of amlodipine

1 reference

12 December 2020

Amlodipine and lisinopril in combination for the treatment of essential hypertension: efficacy and predictors of response

1 reference

12 December 2020

The clinical consequences of the absorption, distribution, metabolism and excretion of amlodipine

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12 December 2020

A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure in hypertensive patients

1 reference

12 December 2020

Comparison of amlodipine and verapamil in the treatment of mild to moderate hypertension

1 reference

12 December 2020

A comparative assessment of amlodipine and felodipine ER: pharmacokinetic and pharmacodynamic indices

1 reference

12 December 2020

A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine

1 reference

12 December 2020

At equipotent doses, isradipine is better tolerated than amlodipine in patients with mild-to-moderate hypertension: a double-blind, randomized, parallel-group study

1 reference

12 December 2020

Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.

1 reference

12 December 2020

Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension

1 reference

12 December 2020

Pharmacologic profile of amlodipine

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12 December 2020

Double-blind, parallel, comparative study on quality of life during treatment with amlodipine or enalapril in mild or moderate hypertensive patients: a multicentre study

1 reference

12 December 2020

Protection of regional mechanics and mitochondrial oxidative phosphorylation by amlodipine in transiently ischemic myocardium

1 reference

12 December 2020

The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload

1 reference

12 December 2020

Comparative effects of amlodipine and felodipine ER on office and ambulatory blood pressure in patients with mild to moderate hypertension. Danish Multicentre Group.

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12 December 2020

Unaltered insulin sensitivity during calcium channel blockade with amlodipine.

1 reference

12 December 2020

Amlodipine in ambulatory hypertensive patients: humoral and haemodynamic effects.

1 reference

12 December 2020

Relaxation of potassium chloride-induced contractions by amlodipine and its interaction with the 1,4-dihydropyridine-binding site in pig coronary artery

1 reference

12 December 2020

[Evaluation of amlodipine in stable effort angina in office cardiologic practice]

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12 December 2020

Effects of amlodipine on myocardial ischemia-reperfusion injury in dogs

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12 December 2020

Antihypertensive treatment and trough: peak ratio: general considerations

1 reference

12 December 2020

Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension

1 reference

12 December 2020

A comparison of the disposition of single oral doses of amlodipine in young and elderly subjects

1 reference

12 December 2020

Amlodipine, a new 1,4-dihydropyridine calcium antagonist with a particularly strong antihypertensive profile

1 reference

12 December 2020

Amlodipine combined with beta blockade for chronic angina: results of a multicenter, placebo-controlled, randomized double-blind study

1 reference

12 December 2020

Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II

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12 December 2020

Effects of amlodipine on myocardial infarction, infarct expansion, and ventricular geometry in the rat

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12 December 2020

Pharmacodynamics of amlodipine: hemodynamic effects and antianginal efficacy after atrial pacing.

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12 December 2020

Erythema multiforme following substitution of amlopidine for nifedipine

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12 December 2020

Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.

1 reference

12 December 2020

Effects of amlodipine on renal haemodynamics in mild to moderate hypertensive patients. A randomized controlled study versus placebo

1 reference

12 December 2020

Pharmacokinetics and additional anti-ischaemic effectiveness of amlodipine, a once-daily calcium antagonist, during acute and long-term therapy of stable angina pectoris in patients pre-treated with a beta-blocker.

1 reference

12 December 2020

1993 guidelines for the management of mild hypertension: memorandum from a World Health Organization/International Society of Hypertension meeting. Guidelines Sub-Committee

1 reference

12 December 2020

Effects of amlodipine on urinary sodium excretion, renin-angiotensin-aldosterone system, atrial natriuretic peptide and blood pressure in essential hypertension

1 reference

12 December 2020

Mechanism of Action of Calcium-Channel-Blocking Agents

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12 December 2020

Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.

1 reference

12 December 2020

Hemodynamic and electrophysiologic effects of amlodipine, a new long-acting calcium antagonist: preliminary observations

1 reference

12 December 2020

Use of drugs with more than a twenty-four-hour duration of action

1 reference

12 December 2020

10.2165/00003495-199550030-00009

Identifiers

DOI

1 reference

PubMed ID

8521773

Dimensions Publication ID

24 September 2017

0 references

1 reference

PubMed ID

8521773