(Q40933612)

English

Lack of responsiveness to TGF-beta1 in a thyroid carcinoma cell line with functional type I and type II TGF-beta receptors and Smad proteins, suggests a novel mechanism for TGF-beta insensitivity in carcinoma cells

scientific article published on July 1999

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Europe PubMed Central

PubMed publication ID

25 September 2017

Lack of responsiveness to TGF-beta1 in a thyroid carcinoma cell line with functional type I and type II TGF-beta receptors and Smad proteins, suggests a novel mechanism for TGF-beta insensitivity in carcinoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

thyroid carcinoma

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based on heuristic

inferred from title

Bengt Westermark

6

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Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

Heldin NE

1

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Europe PubMed Central

PubMed publication ID

25 September 2017

Bergström D

2

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Hermansson A

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Bergenstråhle A

4

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Nakao A

5

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

ten Dijke P

7

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

publication date

1 July 1999

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Molecular and Cellular Endocrinology

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Europe PubMed Central

PubMed publication ID

25 September 2017

153

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Europe PubMed Central

PubMed publication ID

25 September 2017

1-2

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Europe PubMed Central

PubMed publication ID

25 September 2017

79-90

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Europe PubMed Central

PubMed publication ID

25 September 2017

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

1 reference

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7 January 2021

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Culture of hormone-dependent functional epithelial cells from rat thyroids

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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Acquired and naturally occurring resistance of thyroid follicular cells to the growth inhibitory action of transforming growth factor-beta 1 (TGF-beta 1).

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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Loss of responsiveness to transforming growth factor beta (TGFbeta) is tightly linked to tumorigenicity in a model of thyroid tumour progression

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

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Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

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Formation and growth of multicellular spheroids of human origin

1 reference

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7 January 2021

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Transforming growth factor-beta 1 synthesis in human thyroid follicular cells: differential effects of iodide and plasminogen on the production of latent and active peptide forms

1 reference

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7 January 2021

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

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7 January 2021

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

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7 January 2021

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Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

1 reference

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7 January 2021

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Transforming growth factor beta regulates thyroid growth. Role in the pathogenesis of nontoxic goiter

1 reference

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7 January 2021

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Decreased growth rate and tumour formation of human anaplastic thyroid carcinoma cells transfected with a human thyrotropin receptor cDNA in NMRI nude mice treated with propylthiouracil

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Coexpression of Functionally Active Receptors for Thyrotropin and Platelet-Derived Growth Factor in Human Thyroid Carcinoma Cells*

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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Epidermal growth factor, but not thyrotropin, stimulates the expression of c-fos and c-myc messenger ribonucleic acid in porcine thyroid follicle cells in primary culture

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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Transforming growth factor-beta 1 is a negative regulator for differentiated thyroid cancer: studies of growth, migration, invasion, and adhesion of cultured follicular and papillary thyroid cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced expression of transforming growth factor-beta 1 during thyroid hyperplasia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Betaglycan presents ligand to the TGF beta signaling receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of transforming growth factor-beta on growth and differentiation of the continuous rat thyroid follicular cell line, FRTL-5

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of the normal and of the translocated human c-myc oncogenes in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a 60-kDa cell surface-associated transforming growth factor-beta binding protein that can interfere with transforming growth factor-beta receptor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Mad-related genes in the human

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

p53-independent role of MDM2 in TGF-beta1 resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900086-6

7 January 2021

based on heuristic

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The Cystine-Knot Growth-Factor Superfamily

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

General inhibition by transforming growth factor beta 1 of thyrotropin and cAMP responses in human thyroid cells in primary culture

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

1 reference

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Effects of transforming growth factor-beta on deoxyribonucleic acid synthesis and iodine metabolism in porcine thyroid cells in culture

1 reference

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Demonstration That Mutation of the Type II Transforming Growth Factor β Receptor Inactivates Its Tumor Suppressor Activity in Replication Error-positive Colon Carcinoma Cells

1 reference

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7 January 2021

based on heuristic

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Mechanism of activation of the TGF-beta receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0303-7207(99)00086-6

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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