(Q40946216)

25 September 2017

title

The salt-sensitive structure and zinc inhibition of Borrelia burgdorferi protease BbHtrA. (English)

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25 September 2017

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Theresa M Russell

1

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25 September 2017

Xiaoling Tang

2

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25 September 2017

Jason M Goldstein

3

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25 September 2017

Dennis Bagarozzi

4

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25 September 2017

Barbara J B Johnson

5

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25 September 2017

language of work or name

English

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publication date

19 October 2015

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25 September 2017

published in

Molecular Microbiology

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25 September 2017

volume

99

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25 September 2017

issue

3

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25 September 2017

page(s)

586-596

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Characterization of the structure and function of Escherichia coli DegQ as a representative of the DegQ-like proteases of bacterial HtrA family proteins

25 September 2017

cites work

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The HtrA protease from Streptococcus pneumoniae digests both denatured proteins and the competence-stimulating peptide

21 January 2018

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Meta-analysis of the association of the HTRA1 polymorphisms with the risk of age-related macular degeneration

21 January 2018

1 reference

Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

21 January 2018

1 reference

The HtrA Family of Proteases

21 January 2018

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HTRA proteases: regulated proteolysis in protein quality control

21 January 2018

1 reference

The HtrA protease of Borrelia burgdorferi degrades outer membrane protein BmpD and chemotaxis phosphatase CheX.

21 January 2018

1 reference

Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis.

21 January 2018

1 reference

Characterization of an extracellular dipeptidase from Streptococcus gordonii FSS2.

21 January 2018

1 reference

The role of human HtrA1 in arthritic disease

21 January 2018

1 reference

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

21 January 2018

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Factors defining the functional oligomeric state of Escherichia coli DegP protease

21 January 2018

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Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins.

21 January 2018

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Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease

21 January 2018

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Proteolysis of BB0323 results in two polypeptides that impact physiologic and infectious phenotypes in Borrelia burgdorferi

21 January 2018

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Design of potent selective zinc-mediated serine protease inhibitors

21 January 2018

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Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine

21 January 2018

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Structural basis for the regulated protease and chaperone function of DegP

21 January 2018

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HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues

21 January 2018

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The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase

21 January 2018

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Prediction of extracellular proteases of the human pathogen Helicobacter pylori reveals proteolytic activity of the Hp1018/19 protein HtrA

21 January 2018

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Inhibitors of Helicobacter pylori protease HtrA found by 'virtual ligand' screening combat bacterial invasion of epithelia

21 January 2018

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Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

21 January 2018

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Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferi

21 January 2018

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Molecular Adaptation of the DegQ Protease to Exert Protein Quality Control in the Bacterial Cell Envelope

21 January 2018

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Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control

21 January 2018

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HtrA protease family as therapeutic targets

21 January 2018

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The emerging roles of HTRA1 in musculoskeletal disease.

21 January 2018

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Metal-dependent gene regulation in the causative agent of Lyme disease.

21 January 2018

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Manganese and zinc regulate virulence determinants in Borrelia burgdorferi

21 January 2018

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Substrate-induced remodeling of the active site regulates human HTRA1 activity

21 January 2018

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Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components

21 January 2018

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Strategies for the inhibition of serine proteases

21 January 2018

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21 January 2018

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Host-pathogen interactions promoting inflammatory Lyme arthritis: use of mouse models for dissection of disease processes

21 January 2018

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The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/MMI.13251

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25 September 2017

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