Home
Random
Nearby
Log in
Settings
Donate Now
If Wikipedia is useful to you, please give today.
About Wikidata
Disclaimers
Search
(Q40961806)
Watch
English
Caspase-8 is required for cell death induced by expanded polyglutamine repeats.
scientific article published on March 1999
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
title
Caspase-8 is required for cell death induced by expanded polyglutamine repeats
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
main subject
cell death
1 reference
based on heuristic
inferred from title
author
Ivelisse Sanchez
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
author name string
C J Xu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
P Juo
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
A Kakizaka
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
J Blenis
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
J Yuan
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
publication date
1 March 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
language of work or name
English
0 references
published in
Neuron
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
22
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
623-633
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mouse models of neurodegenerative disease caused by CAG/polyglutamine expansions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteases to die for
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of vertebrate neuronal death by the crmA gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal distribution of intranuclear inclusions in Huntington's disease with adult onset.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-X L interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-3 Is Required for α-Fodrin Cleavage but Dispensable for Cleavage of Other Death Substrates in Apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metalloproteinase-mediated release of human Fas ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane Oligomerization and Cleavage Activates the Caspase-8 (FLICE/MACHα1) Death Signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 gene family in the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-x(L) forms an ion channel in synthetic lipid membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dentatorubral Pallidoluysian Atrophy (DRPLA) Protein Is Cleaved by Caspase-3 during Apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An induced proximity model for caspase-8 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9, Bcl-XL, and Apaf-1 Form a Ternary Complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide repeats in neurogenetic disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Channel formation by antiapoptotic protein Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoproteolytic Activation of Pro-Caspases by Oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target protease specificity of the viral serpin CrmA. Analysis of five caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980716-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0896-6273(00)80716-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
PubMed publication ID
10197541
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10197541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10197541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit