(Q41106742)

26 September 2017

title

Sounding the alarm: protein kinase cascades activated by stress and inflammation (English)

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26 September 2017

Kyriakis JM

1

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26 September 2017

Avruch J

series ordinal

2

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26 September 2017

publication date

1 October 1996

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Journal of Biological Chemistry

26 September 2017

language of work or name

English

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published in

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26 September 2017

volume

271

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26 September 2017

issue

40

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26 September 2017

page(s)

24313-24316

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publication type of scholarly work

26 September 2017

review article

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The proliferation of MAP kinase signaling pathways in yeast.

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Phosphorylation of c-jun mediated by MAP kinases.

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An osmosensing signal transduction pathway in yeast.

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

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Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

21 January 2018

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

21 January 2018

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Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

21 January 2018

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

21 January 2018

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

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Components of a new human protein kinase signal transduction pathway

21 January 2018

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

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The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases

21 January 2018

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

21 January 2018

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JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

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Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

21 January 2018

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

21 January 2018

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

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Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

21 January 2018

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

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Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

21 January 2018

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

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Raf meets Ras: completing the framework of a signal transduction pathway

21 January 2018

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

21 January 2018

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Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

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Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

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Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets

21 January 2018

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Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

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Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes.

21 January 2018

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Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae.

21 January 2018

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Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Cloning and characterization of a human protein kinase with homology to Ste20

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

UV irradiation and heat shock mediate JNK activation via alternate pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Protection from natural killer cell-mediated lysis by HLA-G expression on target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Integration of MAP kinase signal transduction pathways at the serum response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.40.24313

21 January 2018

Identifiers

DOI

10.1074/JBC.271.40.24313

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26 September 2017

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