(Q41126383)

English

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

scientific article published on March 1997

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9030615%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9030615%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

S R D'Mello

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

K Borodezt

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

S P Soltoff

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

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publication date

1 March 1997

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9030615%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

1548-1560

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

Insulin-like growth factor 1 supports embryonic nerve cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on rat cerebellar cells in vitro: influence of substratum, potassium concentration and relationship between neurones and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of depolarization in the survival and differentiation of cerebellar granule cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I supports the survival and/or differentiation of multiple types of central nervous system neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide-surface association: the case of PDZ and PTB domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin receptors: a window into neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate sensitivity on glutamate-resistant cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of developmental neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of members of the trk family in the developing postnatal rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenes and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of bovine brain type I phosphatidylinositol kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and function of IRS-1 in insulin signal transmission.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of SH2-containing proteins in cellular signaling by receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Components of signaling pathways for insulin and insulin-like growth factor-I in muscle myoblasts and myotubes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of phosphoinositide 3-kinase from rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death during development of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of potassium on neuronal differentiation in cultures of dissociated newborn rat cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient IGF-I gene expression during the maturation of functionally related central projection neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factor signaling by receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain neurons develop in a serum and glial free environment: effects of transferrin, insulin, insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9030615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.17-05-01548.1997

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573379&resulttype=core&format=json

15 May 2020

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