(Q41176359)

27 September 2017

1 reference

title

Molecular mechanisms of multidrug resistance in cancer chemotherapy (English)

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27 September 2017

multiple drug resistance

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1 reference

Nooter K

1

1 reference

PubMed ID

8880878

27 September 2017

Stoter G

series ordinal

2

1 reference

27 September 2017

1 July 1996

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Pathology, Research and Practice

27 September 2017

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27 September 2017

192

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27 September 2017

768-780

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27 September 2017

7

1 reference

ATP-dependent bacterial transporters and cystic fibrosis: analogy between channels and transporters

27 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Correlation of MDR1 gene expression with chemotherapy in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Cloning and regulation of the rat mdr2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

High expression of the multidrug resistance-associated protein (MRP) in chronic and prolymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Non-P-glycoprotein multidrug resistance in cell lines which are defective in the cellular accumulation of drug

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Structure and expression of the human MDR (P-glycoprotein) gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

The 1991 Merck Frosst Award. Multidrug resistance in small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

P-glycoprotein structure and evolutionary homologies

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Drug resistance mechanisms and MRP expression in response to epirubicin treatment in a human leukaemia cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Identification of distinct P-glycoprotein gene sequences in rat

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug resistance profiles

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Pharmacologic circumvention of multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Molecular analysis of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of a multidrug resistance gene in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Cloning and characterization of a second member of the mouse mdr gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Differing patterns of cross-resistance resulting from exposures to specific antitumour drugs or to radiation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Topoisomerase II in multiple drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Glutathione-s-transferase pi expression in leukaemia: a comparative analysis with mdr-1 data

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Restoration of taxol sensitivity of multidrug-resistant cells by the cyclosporine SDZ PSC 833 and the cyclopeptolide SDZ 280-446

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Pharmacologic interactions between the resistance-modifying cyclosporine SDZ PSC 833 and etoposide (VP 16-213) enhance in vivo cytostatic activity and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

DNA topoisomerase poisons as antitumor drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Identification of members of the P-glycoprotein multigene family

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistant P388 leukemia cells measured by real-time flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Multidrug resistance (mdr) genes in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Multidrug resistance (MDR) genes in haematological malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Clinical relevance of P-glycoprotein expression in haematological malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Clinical trials of agents that reverse multidrug resistance. A literature review

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Phase II study of combining vinblastine and cyclosporin-A to circumvent multidrug resistance in renal cell cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Cloning and characterization of a member of the rat multidrug resistance (mdr) gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Reversal of drug-resistance by cyclosporin-A in a patient with acute myelocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Clinical modulation of multidrug resistance in multiple myeloma: effect of cyclosporine on resistant tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of the multidrug resistance-associated protein (MRP) gene in human lung tumours and normal tissue as determined by in situ hybridisation

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Cyclosporins as drug resistance modifiers

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

A comparison of rhodamine 123 accumulation and efflux in cells with P-glycoprotein-mediated and MRP-associated multidrug resistance phenotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Sequence of mdr3 cDNA encoding a human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

Multidrug resistance in lymphomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980099-9

7 January 2021

10.1016/S0344-0338(96)80099-9

Identifiers

DOI

0 references

PubMed ID

8880878

1 reference

PubMed ID

8880878