(Q41189915)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497245%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

The tryptophan metabolite picolinic acid suppresses proliferation and metabolic activity of CD4+ T cells and inhibits c-Myc activation (English)

1 reference

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28 February 2020

10

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28 February 2020

Ralf L J Schmidt

3

1 reference

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28 February 2020

Franz Ratzinger

4

1 reference

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28 February 2020

Georg Greiner

5

1 reference

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28 February 2020

Gregor Hoermann

7

1 reference

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28 February 2020

author name string

Johanna Prodinger

1

1 reference

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28 February 2020

Lisa J Loacker

2

1 reference

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28 February 2020

Nadine Witzeneder

6

1 reference

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28 February 2020

Sabrina Jutz

8

1 reference

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28 February 2020

Winfried F Pickl

9

1 reference

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28 February 2020

Rodrig Marculescu

11

1 reference

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28 February 2020

Klaus G Schmetterer

12

1 reference

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28 February 2020

publication date

23 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497245%20AND%20SRC:MED&resulttype=core&format=json

Journal of Leukocyte Biology

28 February 2020

published in

1 reference

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28 February 2020

volume

99

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28 February 2020

issue

4

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28 February 2020

page(s)

583-594

1 reference

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The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

28 February 2020

cites work

1 reference

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

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Prevention of allogeneic fetal rejection by tryptophan catabolism

21 January 2018

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IDO and tolerance to tumors

21 January 2018

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Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

21 January 2018

1 reference

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Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

21 January 2018

1 reference

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Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

21 January 2018

1 reference

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Metabolic checkpoints in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Transforming growth factor beta 1 (TGF-beta1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription

21 January 2018

1 reference

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The effects of Cyclosporine A and azathioprine on human T cells activated by different costimulatory signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Concentrations of cyclosporin A and FK506 that inhibit IL-2 induction in human T cells do not affect TGF-beta1 biosynthesis, whereas higher doses of cyclosporin A trigger apoptosis and release of preformed TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The role of c-myc in cellular growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

MYC on the path to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The TOR kinases link nutrient sensing to cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

T cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Abl tyrosine kinases in T-cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Targeting T cell immunometabolism for cancer immunotherapy; understanding the impact of the tumor microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy-inducing genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Cbl-b and itch: key regulators of peripheral T-cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer.

21 January 2018

1 reference

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Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

21 January 2018

1 reference

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Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

21 January 2018

1 reference

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The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.3A0315-135R

21 January 2018

Identifiers

DOI

10.1189/JLB.3A0315-135R

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497245%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference