(Q41345394)

29 September 2017

1 reference

title

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks (English)

1 reference

29 September 2017

M R Lieber

1

1 reference

29 September 2017

U Grawunder

series ordinal

2

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29 September 2017

X Wu

series ordinal

3

1 reference

29 September 2017

M Yaneva

series ordinal

4

1 reference

29 September 2017

1 February 1997

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Current Opinion in Genetics & Development

29 September 2017

1 reference

29 September 2017

7

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29 September 2017

99-104

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29 September 2017

1

1 reference

A novel pathway of DNA end-to-end joining

29 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

A severe combined immunodeficiency mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The scid mutation in mice causes a general defect in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

A DNA-activated protein kinase from HeLa cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Analysis of the mechanism of interaction of simian Ku protein with DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

DNA-dependent ATPase from HeLa cells is related to human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

X-ray--induced breakage and rejoining of human interphase chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Induction and repair of chromosome aberrations in scid cells measured by premature chromosome condensation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The recognition of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

A modified single-strand annealing model best explains the joining of DNA double-strand breaks mammalian cells and cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Genetic analysis of XR-1 mutation in hamster and human hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980116-5

7 January 2021

10.1016/S0959-437X(97)80116-5

Identifiers

DOI

1 reference

29 September 2017

1 reference