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T cell antigen receptor signal transduction
scientific article published on April 1997
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
review article
1 reference
stated in
Europe PubMed Central
title
T cell antigen receptor signal transduction
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
author name string
Qian D
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
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30 September 2017
Weiss A
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
publication date
1 April 1997
1 reference
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Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
published in
Current Opinion in Cell Biology
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stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
page(s)
205-212
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stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
cites work
Signal transduction by lymphocyte antigen receptors
1 reference
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inferred from DOI database lookup
Multiple kinases mediate T-cell-receptor signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
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T cell antigen receptor signal transduction pathways
1 reference
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Crossref
reference URL
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Complex complexes: signaling at the TCR.
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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy
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Crossref
reference URL
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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
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Altered T cell receptor ligands trigger a subset of early T cell signals
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F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling
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7 January 2021
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Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling
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7 January 2021
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alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
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7 January 2021
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Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes
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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
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Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase
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reference URL
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ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
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Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
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Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
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7 January 2021
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Essential role for ZAP-70 in both positive and negative selection of thymocytes
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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
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Syk tyrosine kinase required for mouse viability and B-cell development
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Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase
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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
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7 January 2021
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ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity
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Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance
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A comparison of the interaction of Shc and the tyrosine kinase ZAP-70 with the T cell antigen receptor zeta chain tyrosine-based activation motif
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Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains
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Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase
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Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor
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ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells
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TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck
1 reference
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Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.
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Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function
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Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70.
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based on heuristic
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The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
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Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases
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7 January 2021
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Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation
1 reference
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based on heuristic
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Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Regulation of Zap-70 by Src family tyrosine protein kinases in an antigen-specific T-cell line
1 reference
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Crossref
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Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes
1 reference
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A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells
1 reference
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7 January 2021
based on heuristic
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Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Multiple p21ras effector pathways regulate nuclear factor of activated T cells.
1 reference
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7 January 2021
based on heuristic
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Blocked Ras activation in anergic CD4+ T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective requirement for MAP kinase activation in thymocyte differentiation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
1 reference
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Crossref
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7 January 2021
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A functional T-cell receptor signaling pathway is required for p95vav activity
1 reference
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7 January 2021
based on heuristic
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Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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based on heuristic
inferred from DOI database lookup
Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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A role for CD5 in TCR-mediated signal transduction and thymocyte selection
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
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7 January 2021
based on heuristic
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Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980064-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(97)80064-6
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
PubMed ID
9069257
1 reference
stated in
Europe PubMed Central
PubMed ID
9069257
retrieved
30 September 2017
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