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HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer.
scientific article published on January 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
main subject
immunotherapy
1 reference
based on heuristic
inferred from title
author name string
M L Disis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
M A Cheever
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
publication date
1 January 1997
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Advances in Cancer Research
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
343-371
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic peptides as vaccines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The neu oncogene encodes an epidermal growth factor receptor-related protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
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7 January 2021
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inferred from DOI database lookup
Using a neural network to identify potential HLA-DR1 binding sites within proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
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inferred from DOI database lookup
Demonstration by two-color flow cytometry that tyrosine kinase activity is required for down-modulation of the oncogenic neu receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Humanization of an anti-p185HER2 antibody for human cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-driven long term-cultured T cells proliferate in vivo, distribute widely, mediate specific tumor therapy, and persist long-term as functional memory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunity to oncogenic proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic proteins as tumor antigens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of HER2/neu-overexpressing tumor targets to lymphokine-activated-killer-cell-mediated lysis: evidence for deficiency of binding and post-binding events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifying antigenic T-cell sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligopeptide induction of a cytotoxic T lymphocyte response to HER-2/neu proto-oncogene in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell recognition of oncogene products: a new strategy for immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of breast tumour development in vivo by downregulation of the p185neu receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of beta-2 microglobulin anti-sense oligonucleotides on sensitivity of HER2/neu oncogene-expressing and nonexpressing target cells to lymphocyte-mediated lysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of erbB-2 and its ligands in growth control of malignant breast epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of interferons on the expression of the proto-oncogene HER-2 in human ovarian carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Large-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of anti-self-immunity to cure cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical significance of erbB-2 (HER-2/neu) protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A recombinant Listeria monocytogenes vaccine expressing a model tumour antigen protects mice against lethal tumour cell challenge and causes regression of established tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of anti-p185HER2 immunoliposomes for cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shared T cell epitopes in epithelial tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage infiltrate and prognosis in c-erbB-2-overexpressing breast carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic significance of her-2/neu expression in breast cancer and its relationship to other prognostic factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of antibodies and immunotoxins reactive with HER-2/neu on growth of ovarian and breast cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferating dendritic cell progenitors in human blood
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominance and crypticity of T cell antigenic determinants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dendritic cell system and its role in immunogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/NEU gene amplification.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogene amplification correlates with dense lymphocyte infiltration in human breast cancers: a role for hematopoietic growth factor release by tumor cells?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
neu/HER-2 cDNA vaccination and pregnancy loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased natural killer cell activity correlates with low or negative expression of the HER-2/neu oncogene in patients with breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering high affinity humanized anti-p185HER2/anti-CD3 bispecific F(ab')2 for efficient lysis of p185HER2 overexpressing tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960103-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-230X(08)60103-7
0 references
PubMed ID
9111870
1 reference
stated in
Europe PubMed Central
PubMed ID
9111870
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9111870%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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