(Q41447207)

English

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

scientific article published on 15 November 2010

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scholarly article

1 reference

Europe PubMed Central

30 September 2017

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice (English)

1 reference

Europe PubMed Central

30 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Julien Bricambert

1

1 reference

Europe PubMed Central

30 September 2017

Jonatan Miranda

2

1 reference

Europe PubMed Central

30 September 2017

Fadila Benhamed

3

1 reference

Europe PubMed Central

30 September 2017

Jean Girard

4

1 reference

Europe PubMed Central

30 September 2017

Catherine Postic

5

1 reference

Europe PubMed Central

30 September 2017

Renaud Dentin

6

1 reference

Europe PubMed Central

30 September 2017

language of work or name

0 references

publication date

15 November 2010

1 reference

Europe PubMed Central

30 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

30 September 2017

120

1 reference

Europe PubMed Central

30 September 2017

4316-4331

1 reference

Europe PubMed Central

30 September 2017

12

1 reference

Europe PubMed Central

30 September 2017

Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells

1 reference

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cAMP prevents glucose-mediated modifications of histone H3 and recruitment of the RNA polymerase II holoenzyme to the L-PK gene promoter

1 reference

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1 October 2017

ATP-citrate lyase links cellular metabolism to histone acetylation

1 reference

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Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation

1 reference

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GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation

1 reference

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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells

1 reference

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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

1 reference

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Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

1 reference

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1 October 2017

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

1 reference

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1 October 2017

Obesity, Inflammation, and Insulin Resistance

1 reference

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1 October 2017

Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

The transcriptional regulatory code of eukaryotic cells--insights from genome-wide analysis of chromatin organization and transcription factor binding

1 reference

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Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

The metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

1 reference

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1 October 2017

Increasing prevalence of the metabolic syndrome among u.s. Adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Salt-inducible kinase in steroidogenesis and adipogenesis

1 reference

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1 October 2017

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

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Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

TORCs: transducers of regulated CREB activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

A central role for JNK in obesity and insulin resistance

1 reference

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1 October 2017

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

p300/CBP proteins: HATs for transcriptional bridges and scaffolds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

HATs on and beyond chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

1 October 2017

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

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Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

1 reference

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Acetylation regulates transcription factor activity at multiple levels

1 reference

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11 June 2018

Hepatic glucose sensing via the CREB coactivator CRTC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

Inhibition of histone acetyltransferase function of p300 by PKCdelta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

19 August 2018

Mutations truncating the EP300 acetylase in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993582

2 December 2018

Both coactivator LXXLL motif-dependent and -independent interactions are required for peroxisome proliferator-activated receptor gamma (PPARgamma) function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21084751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21084751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of p300 at serine 89 by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/21084751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI41624

1 reference

Europe PubMed Central

30 September 2017

1 reference

Europe PubMed Central

30 September 2017

1 reference

Europe PubMed Central

30 September 2017

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