(Q41478736)

1 October 2017

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title

Deadly conformations--protein misfolding in prion disease (English)

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1 October 2017

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Horwich AL

1

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1 October 2017

Weissman JS

series ordinal

2

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1 October 2017

language of work or name

English

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publication date

1 May 1997

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1 October 2017

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1 October 2017

89

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1 October 2017

499-510

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1 October 2017

4

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1 October 2017

A suspicious signature

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Termini of Salmonella flagellin are disordered and become organized upon polymerization into flagellar filament.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

The exceptionally small size of the scrapie agent.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Does the agent of scrapie replicate without nucleic acid?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Transmission dynamics and epidemiology of BSE in British cattle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

RECONSTITUTION OF BACTERIAL FLAGELLA IN VITRO.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Salmonella flagella: in vitro reconstruction and over-all shapes of flagellar filaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

A kinetic study of in vitro polymerization of flagellin.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Influenza hemagglutinin: kinetic control of protein function.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Kinetics versus thermodynamics in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Non-genetic propagation of strain-specific properties of scrapie prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Identification of a protein that purifies with the scrapie prion.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Normal host prion protein necessary for scrapie-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Mice devoid of PrP are resistant to scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Variation in the characteristics of 10 mouse-passaged scrapie lines derived from five scrapie-positive sheep.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Structural clues to prion replication

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Prion protein is necessary for normal synaptic function.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie infectivity, fibrils and low molecular weight protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Pathogenesis of Scrapie Virus Infection in the Mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Immunoaffinity purification and neutralization of scrapie prion infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Kuru; clinical, pathological and epidemiological study of an acute progressive degenerative disease of the central nervous system among natives of the Eastern Highlands of New Guinea

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Experimental transmission of a Kuru-like syndrome to chimpanzees

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Unconventional Viruses and the Origin and Disappearance of Kuru

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to beta-pleated sheet configurations

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Self-replication and scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Solid-state NMR studies of the prion protein H1 fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Alternative conformations of amyloidogenic proteins govern their behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Cell-free formation of protease-resistant prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Immune system-dependent and -independent replication of the scrapie agent

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

BSE transmission to macaques

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Inactivation of the scrapie agent by near monochromatic ultraviolet light

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Fatal familial insomnia: clinical and pathologic study of five new cases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Abnormal fibrils from scrapie-infected brain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Separation and properties of cellular and scrapie prion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Recombinant scrapie-like prion protein of 106 amino acids is soluble

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

A cellular gene encodes scrapie PrP 27-30 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Protein disaggregation mediated by heat-shock protein Hsp104.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Novel proteinaceous infectious particles cause scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Further purification and characterization of scrapie prions.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie prions aggregate to form amyloid-like birefringent rods

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Purification and structural studies of a major scrapie prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Molecular biology of prion diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

NMR structure of the mouse prion protein domain PrP(121-231)

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Defective protein folding as a cause of disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

A detergent-free method for purifying caveolae membrane from tissue culture cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Scrapie prion protein contains a phosphatidylinositol glycolipid.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Treatment of amyloidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Regional mapping of prion proteins in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Distinct prion proteins in short and long scrapie incubation period mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

A new variant of Creutzfeldt-Jakob disease in the UK.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980232-9

7 January 2021

10.1016/S0092-8674(00)80232-9

Identifiers

DOI

1 reference

release_oyyl2fmv2ndrtkz5ynwxjfmwaq

1 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oyyl2fmv2ndrtkz5ynwxjfmwaq

24 November 2022

mapped directly with Wikidata item

1 reference