(Q41519362)

English

The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line

scientific article published on November 1993

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scholarly article

1 reference

Europe PubMed Central

2 October 2017

The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line (English)

1 reference

Europe PubMed Central

2 October 2017

1 reference

based on heuristic

inferred from title

author name string

M Schwaninger

1

1 reference

Europe PubMed Central

2 October 2017

R Blume

2

1 reference

Europe PubMed Central

2 October 2017

E Oetjen

3

1 reference

Europe PubMed Central

2 October 2017

W Knepel

4

1 reference

Europe PubMed Central

2 October 2017

publication date

1 November 1993

1 reference

Europe PubMed Central

2 October 2017

number of pages

5

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inferred from page(s)

Naunyn-Schmiedeberg's Archives of Pharmacology

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Europe PubMed Central

2 October 2017

348

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Europe PubMed Central

2 October 2017

541-545

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Europe PubMed Central

2 October 2017

5

1 reference

Europe PubMed Central

2 October 2017

https://scigraph.springernature.com/pub.10.1007/bf00173216

0 references

Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pancreatic islet cell-specific enhancer-like element in the glucagon gene contains two domains binding distinct cellular proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of T-cell signaling pathways by immunophilin drug complexes: are side effects inherent to immunosuppressive properties?

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific disruption of renal function and gene transcription by cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex regulation of the T cell receptor alpha gene: three different modes of triggering induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK506-induced kidney tubular cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin, a calcium/calmodulin-regulated protein phosphatase, in mammalian neuroendocrine cells and neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effects of cyclosporin A on human pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP response element binding proteins: a cornucopia of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the calmodulin-regulated protein phosphatase, calcineurin, in rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine's effect on insulin secretion in patients with kidney transplants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of cyclosporine (sandimmune). VII. Pathophysiology and toxicology of cyclosporine in humans and animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pancreatic Islet-Specific Glucagon G3 Transcription Factors Recognize Control Elements in the Rat Somatostatin and Insulin-I Genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progress towards a molecular understanding of cyclosporin A-mediated immunosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of action of cyclosporin A and FK506

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506

1 reference

https://pubmed.ncbi.nlm.nih.gov/7509460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00173216

1 reference

Europe PubMed Central

2 October 2017

1 reference

Europe PubMed Central

2 October 2017

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