(Q41561820)

3 October 2017

1 reference

title

Human jejunal effective permeability and its correlation with preclinical drug absorption models (English)

1 reference

3 October 2017

Lennernäs H

1

1 reference

3 October 2017

1 July 1997

1 reference

Journal of Pharmacy and Pharmacology

3 October 2017

1 reference

3 October 2017

49

1 reference

3 October 2017

627-638

1 reference

3 October 2017

7

1 reference

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

3 October 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Regional differences in the lipid composition and fluidity of rat colonic brush-border membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

How structural features influence the biomembrane permeability of peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Guts. How to be physiological.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Comparison between permeability coefficients in rat and human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Pharmacokinetic considerations in rational drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The jejunal secretion of histamine is increased in active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The effect of L-leucine on the absorption of levodopa, studied by regional jejunal perfusion in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Intestinal drug absorption during induced net water absorption in man; a mechanistic study using antipyrine, atenolol and enalaprilat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Regional rectal perfusion: a new in vivo approach to study rectal drug absorption in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Kinetics of swelling of compressed cellulose matrices: a mathematical model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The effect of pH and concentration on alpha-methyldopa absorption in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

A practitioner's perspective of the role of quantitative structure-activity analysis in medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Absorption of glucose, sodium, and water by the human jejunum studied by intestinal perfusion with a proximal occluding balloon and at variable flow rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Intestinal absorption and excretion of octapeptides composed of D amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Luminal nutrients alter tight-junction permeability in the rat jejunum: an in vivo perfusion model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Chemical approaches to improve the oral bioavailability of peptidergic molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Nutrient-induced changes in the permeability of the rat jejunal mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Further studies on the perfusion method for measuring intestinal absorption in man: the effects of a proximal occlusive balloon and a mixing segment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Passage of molecules through the wall of the gastrointestinal tract. II. Application of low-molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Lipophilicity in molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Carrier-mediated intestinal transport of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

The effect of surgical bowel manipulation and anesthesia on intestinal glucose absorption in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Active transport of 3-O-methyl-glucose by the small intestine in chronically catheterized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Reversal of multidrug resistance by surfactants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2042-7158.1997.TB06084.X

10.1111/J.2042-7158.1997.TB06084.X

21 January 2018

Identifiers

DOI

1 reference

3 October 2017

1 reference

PubMed ID

9255703