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Cancer cells exhibit a mutator phenotype
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
review article
1 reference
stated in
Europe PubMed Central
title
Cancer cells exhibit a mutator phenotype
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
main subject
phenotype
1 reference
based on heuristic
inferred from title
author name string
Loeb LA
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
publication date
1 January 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
published in
Advances in Cancer Research
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
volume
72
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
page(s)
25-56
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
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The age distribution of cancer and a multi-stage theory of carcinogenesis
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Karyotypic evolution in human malignant melanoma
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Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.
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Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.
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Mutator phenotypes in human colorectal carcinoma cell lines
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Metaphase chromosome anomaly: association with drug resistance and cell-specific products
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A germline substitution in the human MSH2 gene is associated with high-grade dysplasia and cancer in ulcerative colitis
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Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.
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Modification of DNA by reducing sugars: a possible mechanism for nucleic acid aging and age-related dysfunction in gene expression
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Mutational specificity of N-methyl-N-nitrosourea in the lacI gene of Escherichia coli
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The origin of human cancers
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The origin of mutants
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7 January 2021
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Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage
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7 January 2021
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Ha-ras-1 oncogene mutations in mammary epithelial cells do not contribute to initiation of spontaneous mammary tumorigenesis in rats.
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7 January 2021
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Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver
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Microsatellite alterations in plasma DNA of small cell lung cancer patients.
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7 January 2021
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Bacterial mutator genes and the control of spontaneous mutation
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional activation by p53 correlates with suppression of growth but not transformation.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle checkpoints: preventing an identity crisis
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7 January 2021
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The Bloom's syndrome gene product is homologous to RecQ helicases
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7 January 2021
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A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process
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5-Methylcytosine in eukaryotic DNA.
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7 January 2021
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A genetic model for colorectal tumorigenesis
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The origin and development of human tumors studied with cell markers
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7 January 2021
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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
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Crossref
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7 January 2021
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The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure
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7 January 2021
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Mutator phenotype of Werner syndrome is characterized by extensive deletions
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bloom syndrome: an analysis of consanguineous families assigns the locus mutated to chromosome band 15q26.1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection-induced mutations occur in yeast
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptive mutations in Escherichia coli as a model for the multiple mutational origins of tumors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA Repair in Bacteria and Mammalian Cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
p53: at the crossroads of molecular carcinogenesis and risk assessment
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle control and cancer
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
APC mutations in colorectal tumors with mismatch repair deficiency
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts
1 reference
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Crossref
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7 January 2021
based on heuristic
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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation and cancer: statistical study of retinoblastoma
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fidelity of mammalian DNA polymerases
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7 January 2021
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THE TIME DIMENSION IN HISTOLOGY
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7 January 2021
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Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element
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7 January 2021
based on heuristic
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Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rate of depurination of native deoxyribonucleic acid
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7 January 2021
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Heat-induced deamination of cytosine residues in deoxyribonucleic acid
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7 January 2021
based on heuristic
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Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apurinic sites as mutagenic intermediates
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Errors in DNA synthesis: a source of spontaneous mutations
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferation of mutators in A cell population
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular detection of primary bladder cancer by microsatellite analysis
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA polymerase beta gene mutations in human bladder cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutagenic specificity of ultraviolet light
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA mismatch correction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mismatch repair, genetic stability and tumour avoidance
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mismatch repair in replication fidelity, genetic recombination, and cancer biology
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thymidine kinase mutants obtained by random sequence selection
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased error frequency of DNA polymerases from senescent human fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite alterations in serum DNA of head and neck cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The clonal evolution of tumor cell populations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ageing of Clones of Mammalian Cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of GTBP in genetically unstable cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of a mutL homolog in hereditary colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic mapping of a locus predisposing to human colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity and base substitution at the APRT locus in mismatch-repair-proficient and -deficient colorectal carcinoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite instability in human non-melanoma and melanoma skin cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How many mutations are required for tumorigenesis? Implications from human cancer data
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hPMS2 mutant cell line is defective in strand-specific mismatch repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonrandom chromosomal abnormalities in hematologic disorders of man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infidelity of DNA synthesis associated with bypass of apurinic sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency mutagenesis by a DNA methyltransferase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic microsatellite mutations as molecular tumor clocks.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of the DNA repair protein O6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifying tumor suppressor genes in human colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle control of DNA replication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of DNA polymeraseβ mutants with amino acid substitutions located in the C-terminal portion of the enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Incidence of cancer in 161 families affected by ataxia-telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite instability in cancer of the proximal colon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of gene amplification in human cell hybrids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mutation rate and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic alterations during colorectal-tumor development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positional cloning of the Werner's syndrome gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Foundations in cancer research. Chromosomes and cancer: the evolution of an idea.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960699-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-230X(08)60699-5
0 references
PubMed ID
9338073
1 reference
stated in
Europe PubMed Central
PubMed ID
9338073
retrieved
5 October 2017
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