(Q41685068)

7 October 2017

1 reference

title

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins (English)

1 reference

7 October 2017

Geyer M

1

1 reference

PubMed ID

9434896

7 October 2017

Wittinghofer A

series ordinal

2

1 reference

7 October 2017

1 December 1997

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Current Opinion in Structural Biology

7 October 2017

1 reference

7 October 2017

7

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7 October 2017

786-792

1 reference

7 October 2017

6

1 reference

The GTPase superfamily: a conserved switch for diverse cell functions

7 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structure of the human ADP-ribosylation factor 1 complexed with GDP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Definition of the switch surface in the solution structure of Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of RhoA-GDP and its functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Rab7: crystallization of intact and C-terminal truncated constructs complexed with GDP and GppNHp

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Conformational and dynamic differences between N-ras P21 bound to GTPgammaS and to GMPPNP as studied by NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

High frequency (139.5 GHz) electron paramagnetic resonance spectroscopy of the GTP form of p21 ras with selective 17O labeling of threonine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Helix unwinding in the effector region of elongation factor EF-Tu-GDP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Mss4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Ras/Rap effector specificity determined by charge reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Three-dimensional structure of the Ras-interacting domain of RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The structure of the GTPase-activating domain from p50rhoGAP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Ras-catalyzed hydrolysis of GTP: a new perspective from model studies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Structure and mutational analysis of Rab GDP-dissociation inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

Purification of a Ran-interacting protein that is required for protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2897%2980147-9

7 January 2021

10.1016/S0959-440X(97)80147-9

Identifiers

DOI

1 reference

7 October 2017

1 reference

PubMed ID

9434896