(Q41699972)

English

Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

scientific article published on December 1997

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scholarly article

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Europe PubMed Central

7 October 2017

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Europe PubMed Central

Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights (English)

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Europe PubMed Central

7 October 2017

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object named as

R Hardison

1

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author name string

J L Slightom

2

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Europe PubMed Central

7 October 2017

D L Gumucio

3

1 reference

Europe PubMed Central

7 October 2017

M Goodman

4

1 reference

Europe PubMed Central

7 October 2017

N Stojanovic

5

1 reference

Europe PubMed Central

7 October 2017

W Miller

6

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Europe PubMed Central

7 October 2017

language of work or name

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publication date

1 December 1997

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Europe PubMed Central

7 October 2017

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Europe PubMed Central

7 October 2017

205

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Europe PubMed Central

7 October 2017

73-94

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Europe PubMed Central

7 October 2017

1-2

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Europe PubMed Central

7 October 2017

Participation of the human beta-globin locus control region in initiation of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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Transcriptional control of globin gene switching during vertebrate development

1 reference

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7 January 2021

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Human gamma- to beta-globin gene switching in transgenic mice.

1 reference

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7 January 2021

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Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation

1 reference

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7 January 2021

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Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

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Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expression

1 reference

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7 January 2021

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Recent developments in linear-space alignment methods: a survey.

1 reference

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7 January 2021

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A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1 reference

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7 January 2021

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The molecular genetics of human hemoglobin

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7 January 2021

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Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex

1 reference

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7 January 2021

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Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain

1 reference

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7 January 2021

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Human γ-globin genes silenced independently of other genes in the β-globin locus

1 reference

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7 January 2021

based on heuristic

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Synthetic human beta-globin 5'HS2 constructs function as locus control regions only in multicopy transgene concatamers.

1 reference

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7 January 2021

based on heuristic

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Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins.

1 reference

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7 January 2021

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Developmental regulation of human beta-globin gene transcription: a switch of loyalties?

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

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Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

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A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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Nuclease hypersensitive sites in chromatin

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

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The regulation of human globin gene switching

1 reference

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7 January 2021

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Evolutionary strategies for the elucidation of cis and trans factors that regulate the developmental switching programs of the beta-like globin genes

1 reference

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7 January 2021

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Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes

1 reference

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7 January 2021

based on heuristic

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Importance of globin gene order for correct developmental expression.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative analysis of the locus control region of the rabbit beta-like gene cluster: HS3 increases transient expression of an embryonic epsilon-globin gene

1 reference

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7 January 2021

based on heuristic

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Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

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inferred from DOI database lookup

The gamma-globin genes and their flanking sequences in primates: findings with nucleotide sequences of capuchin monkey and tarsier.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and function of the murine beta-globin locus control region 5' HS-3

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the beta-globin locus control region. Domain opening and synergism between HS2 and HS3.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear scaffold attachment sites in the human globin gene complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The mouse beta-globin locus control region: hypersensitive sites 3 and 4

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Replication structure of the human beta-globin gene domain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The proximal element of the beta globin locus control region is not functionally required in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel DNA-binding protein, HS2NF5, interacts with a functionally important sequence of the human beta-globin locus control region

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Primary structure of the goat beta-globin locus control region.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental silencing of the embryonic zeta-globin gene: concerted action of the promoter and the 3'-flanking region combined with stage-specific silencing by the transcribed segment

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human gamma- to beta-globin gene switching using a mini construct in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of beta-globin gene expression: straightening out the locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of globin gene expression in erythroid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The SWI-SNF complex: a chromatin remodeling machine?

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of gene order in developmental control of human gamma- and beta-globin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypersensitive site 4 of the human beta globin locus control region

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional activation by hypersensitive site three of the human beta-globin locus control region in murine erythroleukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Autonomous developmental control of human embryonic globin gene switching in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Erythroid differentiation of mouse erythroleukemia cells results in reorganization of protein-DNA complexes in the mouse beta maj globin promoter but not its distal enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental regulation of topoisomerase II sites and DNase I-hypersensitive sites in the chicken beta-globin locus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Information content of binding sites on nucleotide sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The complete sequences of the galago and rabbit beta-globin locus control regions: extended sequence and functional conservation outside the cores of DNase hypersensitive sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human hemoglobin switching

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental regulation of human gamma-globin genes in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Sheltering of gamma-globin expression from position effects requires both an upstream locus control region and a regulatory element 3' to the A gamma-globin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Detailed analysis of the site 3 region of the human beta-globin dominant control region

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolution of a fetal expression pattern via cis changes near the gamma globin gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human globin locus activation region (LAR): role in temporal control

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel developmental regulatory motif required for stage-specific activation of the epsilon-globin gene and nuclear factor binding in embryonic erythroid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional enhancers act in cis to suppress position-effect variegation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription complex stability and chromatin dynamics in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of EKLF in human beta-globin gene competition.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

High affinity YY1 binding motifs: identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human beta globin cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A 5' beta-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2897%2900474-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0378-1119(97)00474-5

1 reference

Europe PubMed Central

7 October 2017

1 reference

Europe PubMed Central

7 October 2017

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