(Q41720915)

8 October 2017

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title

The construction of metal centers in proteins by rational design (English)

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8 October 2017

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Hellinga HW

1

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8 October 2017

1 January 1998

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8 October 2017

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8 October 2017

3

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8 October 2017

R1-8

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8 October 2017

1

1 reference

Structural and Functional Aspects of Metal Sites in Biology

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Metalloprotein design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Metal-binding sites in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

The design of metal-binding sites in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Protein design: novel metal-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Engineering metal-binding sites in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Protein design: a hierarchic approach.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Protein design, a minimalist approach.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Incorporation of a stabilizing Ca(2+)-binding loop into subtilisin BPN'

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Grafting of a calcium-binding loop of thermolysin to Bacillus subtilis neutral protease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Design and creation of a Ca2+ binding site in human lysozyme to enhance structural stability

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Entropic stabilization of a mutant human lysozyme induced by calcium binding

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Stability effects associated with the introduction of a partial and a complete Ca(2+)-binding site into human lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Grafting of a high-affinity Zn(II)-binding site on the beta-barrel of retinol-binding protein results in enhanced folding stability and enables simplified purification

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Metal ion-dependent modulation of the dynamics of a designed protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Identification of the molecular trigger for allosteric activation in glycogen phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

X-ray structures of a designed binding site in trypsin show metal-dependent geometry

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Engineered metal regulation of trypsin specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Delocalizing trypsin specificity with metal activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Regulation of serine protease activity by an engineered metal switch

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Structure of an engineered, metal-actuated switch in trypsin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Designed protein pores as components for biosensors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

A Fluorescent Zinc Probe Based on Metal-Induced Peptide Folding

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Characterization of metal binding by a designed protein: single ligand substitutions at a tetrahedral Cys2His2 site

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Novel metal-binding proteins by design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

A tetrahedral zinc(II)-binding site introduced into a designed protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Design and synthesis of multi-haem proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Introduction of a [4Fe-4S (S-cys)4]+1,+2 iron-sulfur center into a four-alpha helix protein using design parameters from the domain of the Fx cluster in the Photosystem I reaction center

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

The rational design and construction of a cuboidal iron-sulfur protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Ferredoxin and ferredoxin-heme maquettes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Construction of a catalytically active iron superoxide dismutase by rational protein design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

A designed metal-binding protein with a novel fold

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

High level expression and rational mutagenesis of a designed protein, the minibody. From an insoluble to a soluble molecule.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Cu(II)-binding properties of a cytochrome c with a synthetic metal-binding site: His-X3-His in an alpha-helix

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Characterization of His-X3-His sites in α-helices of synthetic metal-binding bovine somatotropin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Metalloantibody design.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

1 reference

7 January 2021

Construction of new ligand binding sites in proteins of known structure. II. Grafting of a buried transition metal binding site into Escherichia coli thioredoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Scorpion toxins as natural scaffolds for protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Engineered metal-binding proteins: purification to protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Metal search: a computer program that helps design tetrahedral metal-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Construction of new ligand binding sites in proteins of known structure

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Desperately seeking sensors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Calcium-binding sites in proteins: a structural perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

The galvanization of biology: a growing appreciation for the roles of zinc

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Structural Biology of Zinc

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Characterization of a helical protein designed from first principles

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Global topology & stability and local structure & dynamics in a synthetic spin-labeled four-helix bundle protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Structural and electronic properties of the heme cofactors in a multi-heme synthetic cytochrome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Protein Control of Redox Potentials of Ironminus signSulfur Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Design and characterization of a ligand-binding metallopeptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

Electrostatic recognition between superoxide and copper, zinc superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900001-7

7 January 2021

10.1016/S1359-0278(98)00001-7

Identifiers

DOI

1 reference

8 October 2017

1 reference

PubMed ID

9502313