(Q41753871)

English

The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration?

scientific article published on May 1998

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scholarly article

1 reference

Europe PubMed Central

8 October 2017

1 reference

Europe PubMed Central

The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration? (English)

1 reference

Europe PubMed Central

8 October 2017

Alzheimer's disease

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author name string

Small DH

1

1 reference

Europe PubMed Central

8 October 2017

publication date

1 May 1998

1 reference

Europe PubMed Central

8 October 2017

Neurochemical Research

1 reference

Europe PubMed Central

8 October 2017

23

1 reference

Europe PubMed Central

8 October 2017

795-806

1 reference

Europe PubMed Central

8 October 2017

5

1 reference

Europe PubMed Central

8 October 2017

https://scigraph.springernature.com/pub.10.1023/a:1022471729291

0 references

Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The topography of plaques and tangles in Down's syndrome patients of different ages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The promoter of Alzheimer's disease amyloid A4 precursor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An interaction between basement membrane and Alzheimer amyloid precursor proteins suggests a role in the pathogenesis of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The olfactory bulbs in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial expression, purification, and functional mapping of the amyloid beta/A4 protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein potentiates Ca2+ influx through L-type voltage-sensitive Ca2+ channels: a possible involvement of free radicals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular analysis of associative learning

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of protease nexin II from human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid protein promotes neuritic branching in hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mab22C11 antibody to amyloid precursor protein recognizes a protein associated with specific astroglial cells of the rat central nervous system characterized by their capacity to support axonal outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide (A beta P) potentiates a nimodipine-sensitive L-type barium conductance in N1E-115 neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of inflammation and cytokines in brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of beta-amyloid protein precursor and microtubule-associated protein tau during the differentiation of murine embryonal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor potentiates the neurotoxicity of beta amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of the Swedish APP670/671 mutation for the development of Alzheimer's disease amyloidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrolysis of amyloid precursor protein-derived peptides by cysteine proteinases and extracts of rat brain clathrin-coated vesicles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of cell populations in the olfactory epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased beta-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitters in the regulation of neuronal cytoarchitecture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo neuronal synthesis and axonal transport of Kunitz protease inhibitor (KPI)-containing forms of the amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of beta-amyloid precursor protein and ubiquitin in axons after spinal cord trauma in humans: immunohistochemical observations on autopsy material.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A head impact model of early axonal injury in the sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally Occurring Degrading Events in Axon Terminals of the Dentate Gyrus and Stratum lucidum in the Spiny Mouse <i>(Acomys cahirinus)</i> during Maturation, Adulthood and Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended pedigrees with early onset Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary perspectives on amyloid and inflammatory features of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of beta-amyloid precursor by calpain I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease and other dementing illnesses in a defined United States population: incidence rates and clinical features

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of amyloid precursor protein in GAP43-immunoreactive aberrant sprouting neurites in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid precursor protein of Alzheimer's disease is released by human platelets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presenilin genes: a new gene family involved in Alzheimer disease pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease nexin I immunostaining in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of neurite growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer amyloid beta/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological basis of long-term habituation and sensitization in Aplysia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic organization of the human amyloid beta-protein precursor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of presenillin 1 gene in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress after acute and chronic application of beta-amyloid fragment 25-35 in cortical cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraventricular infusions of antibodies to amyloid-beta-protein precursor impair the acquisition of a passive avoidance response in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Markers of axonal injury in post mortem human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal degeneration promotes abnormal accumulation of amyloid beta-protein in ascending gracile tract of gracile axonal dystrophy (GAD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-1 polymorphism in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia in Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of proteoglycans in neural development, regeneration, and the aging brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrically and chemically mediated increases in intracellular calcium in neuronal growth cones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochalasins protect hippocampal neurons against amyloid beta-peptide toxicity: evidence that actin depolymerization suppresses Ca2+ influx.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topography of Axonal Injury as Defined by Amyloid Precursor Protein and the Sector Scoring Method in Mild and Severe Closed Head Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta amyloid protein (AD-AP) cDNA hybridizes in normal and Alzheimer individuals near the interface of 21q21 and q22.1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta peptide, substance P, and bombesin bind to the serpin-enzyme complex receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between vascular basement membrane components and the lesions of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory reaction in experimental autoimmune encephalomyelitis (EAE) is accompanied by a microglial expression of the beta A4-amyloid precursor protein (APP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of basic Fibroblast Growth Factor in Alzheimerʼs disease pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease amyloid beta-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: the role of the complement system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beta-amyloid precursor protein in the developing human spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Olfactory bulb changes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A presenilin 1 mutation in an early onset Alzheimer's family: no association with presenilin 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paired helical filament tau in Alzheimer's disease. The kinase connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathological association between Down syndrome and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of injected Alzheimer beta-amyloid cores in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial Alzheimer's chromosome 14 mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-way cleavage of β-amyloid protein precursor by multicatalytic proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9566620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1022471729291

1 reference

Europe PubMed Central

8 October 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

8 October 2017

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