(Q41911731)

14 October 2017

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title

Metallocenes and malaria: a new therapeutic approach (English)

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14 October 2017

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Pradines B

1

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14 October 2017

Orlandi-Pradines E

2

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14 October 2017

Henry M

3

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14 October 2017

Bogreau H

4

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14 October 2017

Fusai T

5

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14 October 2017

Mosnier J

6

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14 October 2017

Baret E

7

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14 October 2017

Durand C

8

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14 October 2017

Bouchiba H

9

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14 October 2017

Penhoat K

10

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14 October 2017

Rogier C

11

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14 October 2017

publication date

1 August 2005

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Annales pharmaceutiques françaises

14 October 2017

published in

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14 October 2017

volume

63

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14 October 2017

issue

4

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14 October 2017

page(s)

284-294

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Chloroquine-resistant malaria

14 October 2017

cites work

1 reference

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7 January 2021

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Metal complexes for therapy and diagnosis of drug resistance.

7 January 2021

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Toward a novel metal-based chemotherapy against tropical diseases. 2. Synthesis and antimalarial activity in vitro and in vivo of new ruthenium- and rhodium-chloroquine complexes

7 January 2021

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Toward a novel metal-based chemotherapy against tropical diseases. 3. Synthesis and antimalarial activity in vitro and in vivo of the new gold-chloroquine complex [Au(PPh3)(CQ)]PF6.

7 January 2021

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Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

7 January 2021

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Synthesis of ferroquine enantiomers: first investigation of effects of metallocenic chirality upon antimalarial activity and cytotoxicity.

7 January 2021

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In vitro and in vivo antimalarial activity of ferrochloroquine, a ferrocenyl analogue of chloroquine against chloroquine-resistant malaria parasites

7 January 2021

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Ferrocene-chloroquine analogues as antimalarial agents: in vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum

7 January 2021

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In vitro activities of ferrochloroquine against 55 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs

7 January 2021

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In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon

7 January 2021

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The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum

7 January 2021

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Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

7 January 2021

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Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle

7 January 2021

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A microtitre-based method for measuring the haem polymerization inhibitory activity (HPIA) of antimalarial drugs

7 January 2021

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Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth

7 January 2021

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Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

7 January 2021

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A molecular marker for chloroquine-resistant falciparum malaria

7 January 2021

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Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum

7 January 2021

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Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX.

7 January 2021

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Synthetic ferrocenic mefloquine and quinine analoguesas potential antimalarial agents.

7 January 2021

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Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

7 January 2021

1 reference

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A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole

7 January 2021

1 reference

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Nucleotide binding properties of a P-glycoprotein homologue from Plasmodium falciparum

7 January 2021

1 reference

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Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance.

7 January 2021

1 reference

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Plasmodium falciparum: in vitro chloroquine susceptibility and allele-specific PCR detection of Pfmdr1 Asn86Tyr polymorphism in Lambarene, Gabon

7 January 2021

1 reference

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Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene

7 January 2021

1 reference

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Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes

7 January 2021

1 reference

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Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand

7 January 2021

1 reference

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The structure of malaria pigment beta-haematin

7 January 2021

1 reference

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An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials

7 January 2021

1 reference

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Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerization in Plasmodium falciparum in vitro.

7 January 2021

1 reference

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Haemolysis of Plasmodium falciparum trophozoite-infected erythrocytes after artemisinin exposure

7 January 2021

1 reference

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Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite

7 January 2021

1 reference

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Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations

7 January 2021

1 reference

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Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains.

7 January 2021

1 reference

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Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum

7 January 2021

1 reference

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Synthesis of novel ferrocenyl sugars and their antimalarial activities

7 January 2021

1 reference

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Effects of zinc-desferrioxamine on Plasmodium falciparum in culture

7 January 2021

1 reference

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Parasite uptake of desferroxamine: a prerequisite for antimalarial activity

7 January 2021

1 reference

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The antimalarial action of desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites

7 January 2021

1 reference

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Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine.

7 January 2021

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Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

7 January 2021

1 reference

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Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

7 January 2021

1 reference

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An iron-carboxylate bond links the heme units of malaria pigment

7 January 2021

1 reference

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Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Non-iron porphyrins inhibit beta-haematin (malaria pigment) polymerisation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

A novel endogenous antimalarial: Fe(II)-protoporphyrin IX alpha (heme) inhibits hematin polymerization to beta-hematin (malaria pigment) and kills malaria parasites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Metalloporphyrins inhibit beta-hematin (hemozoin) formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Possible modes of action of the artemisinin-type compounds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Reaction of antimalarial endoperoxides with specific parasite proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Alkylation of proteins by artemisinin. Effects of heme, pH, and drug structure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Enhancement of hemin-induced membrane damage by artemisinin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-4509%2805%2982293-X

Molecular modeling studies of the artemisinin (qinghaosu)-hemin interaction: docking between the antimalarial agent and its putative receptor

7 January 2021

1 reference

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10.1016/S0003-4509(05)82293-X

7 January 2021

Identifiers

DOI

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14 October 2017

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