(Q42102435)

16 October 2017

Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome (English)

1 reference

16 October 2017

Cristina Ticu

1

1 reference

16 October 2017

Roxana Nechifor

2

1 reference

16 October 2017

Boray Nguyen

3

1 reference

16 October 2017

Melanie Desrosiers

4

1 reference

16 October 2017

Kevin S Wilson

5

1 reference

16 October 2017

language of work or name

English

0 references

publication date

18 June 2009

1 reference

16 October 2017

1 reference

16 October 2017

28

1 reference

16 October 2017

14

1 reference

16 October 2017

2053-2065

1 reference

The ribosome as a conveying thermal ratchet machine

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Ribosomal translocation: one step closer to the molecular mechanism

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Irreversible chemical steps control intersubunit dynamics during translation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Spontaneous intersubunit rotation in single ribosomes.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

The process of mRNA-tRNA translocation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Kinetically competent intermediates in the translocation step of protein synthesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structural insights into translational fidelity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Locking and unlocking of ribosomal motions

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

The guanine nucleotide-binding switch in three dimensions

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

A ratchet-like inter-subunit reorganization of the ribosome during translocation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Dynamics of translation on the ribosome: molecular mechanics of translocation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

An alpha to beta conformational switch in EF-Tu

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Crystal structure of active elongation factor Tu reveals major domain rearrangements

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Three-dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Polypeptide Chain Elongation in Protein Biosynthesis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Ribosomal translocation: facts and models

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Intermediate states in the movement of transfer RNA in the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

The role of guanosine 5′-triphosphate in polypeptide chain elongation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Studies on translocation. 21. Steady state kinetic analysis of the mechanism of guanosine triphosphate hydrolysis catalyzed by Escherichia coli elongation factor G and the ribosome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Absolute in vivo translation rates of individual codons in Escherichia coli. The two glutamic acid codons GAA and GAG are translated with a threefold difference in rate.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Functional interactions between the G' subdomain of bacterial translation factor EF-G and ribosomal protein L7/L12.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

The antibiotic viomycin traps the ribosome in an intermediate state of translocation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Structural insights into fusidic acid resistance and sensitivity in EF-G.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Interaction of helix D of elongation factor Tu with helices 4 and 5 of protein L7/12 on the ribosome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Interactions of translational factor EF-G with the bacterial ribosome before and after mRNA translocation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Principles and methods of affinity cleavage in studying transcription

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Peptidyl-tRNA regulates the GTPase activity of translation factors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

GTPase activation of elongation factors Tu and G on the ribosome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Elongation factor G with effector loop from elongation factor Tu is inactive in translocation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Kinetic mechanism of elongation factor Ts-catalyzed nucleotide exchange in elongation factor Tu.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718289

Composition and Properties of Trypsin-Cleaved Elongation Factor Tu

17 August 2018

1 reference

12 December 2020

Altered sensitivity of eukaryotic elongation factor 2 for trypsin after phosphorylation and ribosomal binding

1 reference

12 December 2020

Synergism between the GTPase activities of EF-Tu.GTP and EF-G.GTP on empty ribosomes. Elongation factors as stimulators of the ribosomal oscillation between two conformations

1 reference

12 December 2020

The conformational properties of elongation factor G and the mechanism of translocation

1 reference

12 December 2020

Crosslinking of translation factor EF-G to proteins of the bacterial ribosome before and after translocation

1 reference

12 December 2020

Translocation. XV. Characteristics of and structural requirements for the interaction of 24,25-dihydrofusidic acid with ribosome.elongation factor G complexes

1 reference

12 December 2020

Limited trypsinolysis of native Escherichia coli elongation factor G

1 reference

12 December 2020

Binding interactions between radiolabeled Escherichia coli elongation factor G and the ribosome

1 reference

12 December 2020

Equilibrium measurements of the interactions of guanine nucleotides with Escherichia coli elongation factor G and the ribosome

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.169

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

19536129

1 reference