(Q422360)

EF-hand domain pair

1 reference

SPARC

1 reference

Follistatin/Osteonectin EGF domain, protein family

1 reference

Follistatin-like, N-terminal domain, protein family

1 reference

SPARC/testican, calcium-binding domain, protein family

1 reference

Kazal domain, protein family

1 reference

Osteonectin-like, conserved site, protein family

1 reference

EF-Hand 1, calcium-binding site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

3 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

1 January 2018

Osteonectin, a bone-specific protein linking mineral to collagen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

protein binding

4 references

8 April 2019

Structural basis of sequence-specific collagen recognition by SPARC

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Complex formation of human thrombospondin with osteonectin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

collagen binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

3 references

1 January 2018

1 January 2018

Osteonectin, a bone-specific protein linking mineral to collagen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

1 January 2018

Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

extracellular matrix structural constituent

HDA

1 reference

1 January 2018

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

HDA

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Osteonectin, a bone-specific protein linking mineral to collagen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

IBA

collagen binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

4 references

8 April 2019

8 April 2019

Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Osteonectin, a bone-specific protein linking mineral to collagen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

extracellular matrix structural constituent

IBA

RCA

1 reference

8 April 2019

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

RCA

cell component

cytoplasm

4 references

8 April 2019

Investigation of osteocalcin, osteonectin, and dentin sialophosphoprotein in developing human teeth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Spreading of embryologically distinct urothelial cells is inhibited by SPARC

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

Osteonectin/SPARC/BM-40 in human decidua and carcinoma, tissues characterized by de novo formation of basement membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

platelet alpha granule

1 reference

8 April 2019

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

endocytic vesicle lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

nuclear matrix

1 reference

8 April 2019

Spreading of embryologically distinct urothelial cells is inhibited by SPARC

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

plasma membrane

1 reference

8 April 2019

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

intracellular anatomical structure

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

basement membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

cell surface

platelet alpha granule membrane

1 reference

8 April 2019

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

mitochondrion

1 reference

8 April 2019

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

platelet alpha granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

nucleus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

extracellular space

IBA

3 references

vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

4 references

1 January 2018

1 January 2018

The human plasma proteome: a nonredundant list developed by combination of four separate sources

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

1 January 2018

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

4 references

8 April 2019

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

8 April 2019

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

HDA

extracellular matrix

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

biological process

response to cytokine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to cadmium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

ossification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

lung development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

cellular response to growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to peptide hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

platelet degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

extracellular matrix organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

response to L-ascorbic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to glucocorticoid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

wound healing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

receptor-mediated endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

1 reference

8 April 2019

negative regulation of endothelial cell proliferation

1 reference

8 April 2019

Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

positive regulation of endothelial cell migration

1 reference

8 April 2019

Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to gravity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

heart development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to lead ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

negative regulation of angiogenesis

1 reference

8 April 2019

Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

inner ear development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

regulation of cell morphogenesis

1 reference

8 April 2019

Spreading of embryologically distinct urothelial cells is inhibited by SPARC

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to cAMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

response to ethanol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

bone development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09486&geneProductId=UniProtKB:P09486

1 reference

1 January 2018

pigmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

regulation of synapse organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09486

http://purl.uniprot.org/uniprot/P09486

Gene Atlas image

PBB GE SPARC 200665 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

EF-hand 1, calcium-binding site

Identifiers.org

has part(s)

1 reference

Kazal domain

1 reference

follistatin-like, N-terminal

1 reference

osteonectin-like, conserved site

1 reference

SPARC/testican, calcium-binding domain

1 reference

follistatin/osteonectin EGF domain

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

MeSH descriptor ID

C577241

subject named as

SPARC protein, human

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

0 references

0 references

1 reference

26 January 2022

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023