(Q42279080)

15 June 2018

title

Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice (English)

1 reference

15 June 2018

author name string

F Kari

1

1 reference

15 June 2018

J Bucher

2

1 reference

15 June 2018

J Haseman

3

1 reference

15 June 2018

S Eustis

4

1 reference

15 June 2018

J Huff

5

1 reference

15 June 2018

publication date

1 March 1995

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15 June 2018

number of pages

12

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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15 June 2018

volume

86

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15 June 2018

page(s)

252-263

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15 June 2018

issue

3

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15 June 2018

Di(2-ethylhexyl) adipate: Condensation of the Carcinogenesis Bioassay Technical Report

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1 reference

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Absence of morphologic correlation between chemical toxicity and chemical carcinogenesis

16 June 2018

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Analgesics and cancer of the renal pelvis in New South Wales

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Renal pelvic neoplasms and atypical urothelium in patients with end-stage analgesic nephropathy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Adenocarcinoma of the kidney. III. Histogenesis of renal adenocarcinomas induced in rats by N-(4'-fluoro-4-biphenylyl)acetamide

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Pathology requirements for two-year rodent studies II. Alternative approaches

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Pathology requirements for rodent two-year studies. I. A review of current procedures

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Statistical issues in the design, analysis and interpretation of animal carcinogenicity studies

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Salmonella mutagenicity test results for 250 chemicals

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Chromosomal studies in patients taking phenylbutazone

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Influence of body weight on the incidence of spontaneous tumors in rats and mice of long-term studies.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Long-term studies on carcinogenicity and promoting effect of phenylbutazone in DONRYU rats

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Cellular origin of rat renal oncocytoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Analgesic use and chronic renal disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Chemicals associated with site-specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Chemical toxicity and chemical carcinogenesis. Is there a causal connection? A comparative morphological evaluation of 1500 experiments

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Predictive value of hepatic preneoplastic lesions as indicators of carcinogenic response

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Further studies of the acute effects of phenylbutazone, oxyphenbutazone and indomethacin on the rat kidney

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Experimental renal papillary necrosis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Statistical issues in interpretation of chronic bioassay tests for carcinogenicity

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Histopathological studies on renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Pharmacological mechanisms of analgesic nephropathy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Toxicology and carcinogenesis studies of o-nitrotoluene sulfone (CAS no. 88-72-2) in F344/N rats and B6C3F(1) mice (feed studies).

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Critique does not validate assumptions in the model on alpha 2u-globulin and renal carcinogenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5920813

Phenylbutazone (butazolidin); effect on basal gastric secretion and the production of gastroduodenal ulcerations in dogs

17 August 2018

1 reference

12 December 2020

Interpretation of Rodent Hepatocellular Proliferative Alterations and Hepatocellular Tumors in Chemical Safety Assessment 1 , 2.

1 reference

12 December 2020

Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines

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12 December 2020

Site-specific renal cytotoxicity and cell proliferation in male rats exposed to petroleum hydrocarbons

1 reference

12 December 2020

Possible involvement of non-steroidal anti-inflammatory drugs in vagal-mediated gastric acid secretion in rats

1 reference

12 December 2020

Lesions in the blood supply of the papilla in experimental analgesic nephropathy

1 reference

12 December 2020

Experimental renal papillary necrosis. Effects of diuresis and antidiuresis

1 reference

12 December 2020

Chromosome studies before and after phenylbutazone infusion therapy

1 reference

12 December 2020

Carcinogenicity of potassium bromate administered orally to F344 rats

1 reference

12 December 2020

Phenylbutazone-induced nephrotoxicity in the rat

1 reference

12 December 2020

Phenylbutazone toxicosis in the foal

1 reference

12 December 2020

Effects of toxic doses of phenylbutazone in ponies

1 reference

12 December 2020

Transitional cell carcinoma: rapid development in phenacetin abuse

1 reference

12 December 2020

Sequential observations on the appearance of neoplastic lesions in the liver and kidney after treatment with N-ethyl-N-hydroxyethylnitrosamine followed by partial hepatectomy and unilateral nephrectomy

1 reference

12 December 2020

Role of urinary concentrating ability in the generation of toxic papillary necrosis

1 reference

12 December 2020

Patterns of tumor incidence in two-year cancer bioassay feeding studies in Fischer 344 rats

1 reference

12 December 2020

Synergism between acid and gastric contractile activity in the genesis of ulceration and hemorrhage in the phenylbutazone-treated rat

1 reference

12 December 2020

Analgesic-associated nephropathy and transitional cell carcinoma of the urinary tract

1 reference

12 December 2020

Induction of micronuclei in bone marrow cells of mice treated with phenylbutazone

1 reference

12 December 2020

Influence of dietary protein concentration on severity of nephropathy in Fischer-344 (F-344/N) rats

1 reference

12 December 2020

10.1111/J.1349-7006.1995.TB03048.X

Identifiers

DOI

1 reference

15 June 2018

PMCID

5920813

1 reference

15 June 2018

PubMed ID

7744695

1 reference

15 June 2018