(Q42470731)

1 November 2017

Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1. (English)

1 reference

1 November 2017

Rojas JM

1

1 reference

1 November 2017

Subleski M

2

1 reference

1 November 2017

Coque JJ

3

1 reference

1 November 2017

Guerrero C

4

1 reference

1 November 2017

Saez R

5

1 reference

1 November 2017

Li BQ

6

1 reference

1 November 2017

Lopez E

7

1 reference

1 November 2017

Zarich N

8

1 reference

1 November 2017

Aroca P

9

1 reference

1 November 2017

Kamata T

10

1 reference

1 November 2017

Santos E

11

1 reference

1 November 2017

language of work or name

English

0 references

publication date

1 March 1999

1 reference

1 November 2017

1 reference

1 November 2017

18

1 reference

1 November 2017

1651-1661

1 reference

1 November 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202483

1 November 2017

0 references

cites work

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Regulation of Sos activity by intramolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

The GRB2/Sem-5 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Isolated Sos1 PH domain exhibits germinal vesicle breakdown-inducing activity in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Signal transduction in T lymphocytes using a conditional allele of Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

In vivo functional analysis of the Ras exchange factor son of sevenless

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

ras p21 deletion mutants and monoclonal antibodies as tools for localization of regions relevant to p21 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Signal transduction. How receptors turn Ras on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Phosphatidylinositol 3-kinase activity is important for progesterone-induced Xenopus oocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

How receptor tyrosine kinases activate Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

The Grb2 binding domain of mSos1 is not required for downstream signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

The pathway to signal achievement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

7 January 2021

Laser treatment of port-wine stains and hemangiomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

7 January 2021

Ras p21 as a potential mediator of insulin action in Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

7 January 2021

Applications of interaction traps/two-hybrid systems to biotechnology research

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202483

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202483

1 reference

Dimensions Publication ID

1 November 2017

0 references

1 reference