(Q42522063)

1 November 2017

title

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response (English)

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1 November 2017

P Wei

1

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1 November 2017

J Zhang

2

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1 November 2017

D H Dowhan

3

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1 November 2017

Y Han

4

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1 November 2017

D D Moore

5

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1 November 2017

publication date

1 January 2002

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The Pharmacogenomics Journal

1 November 2017

published in

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1 November 2017

volume

2

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1 November 2017

issue

2

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1 November 2017

page(s)

117-126

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Phenobarbital induction of cytochrome P-450 gene expression

1 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Induction and drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

CYP3A gene expression in human gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The role of individual human cytochromes P450 in drug metabolism and clinical response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

Induction of hepatic CYP2B in foetal and neonatal rats after maternal administration of phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500087

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.TPJ.6500087

1 reference

1 November 2017

1 reference