(Q42659660)

4 November 2017

Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site (English)

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4 November 2017

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Raffaele De Francesco

object named as

Raffaele De Francesco

9

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author name string

Stefania Di Marco

1

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4 November 2017

Cinzia Volpari

2

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4 November 2017

Licia Tomei

3

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4 November 2017

Sergio Altamura

4

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4 November 2017

Steven Harper

5

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4 November 2017

Frank Narjes

6

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4 November 2017

Uwe Koch

7

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4 November 2017

Michael Rowley

8

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4 November 2017

Giovanni Migliaccio

10

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4 November 2017

Andrea Carfí

11

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4 November 2017

language of work or name

English

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publication date

13 June 2005

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Journal of Biological Chemistry

4 November 2017

6

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based on heuristic

inferred from page(s)

published in

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4 November 2017

280

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4 November 2017

29765-29770

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4 November 2017

33

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Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

4 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

The scientific challenge of hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Mechanism of de novo initiation by the hepatitis C virus RNA-dependent RNA polymerase: role of divalent metals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Selection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

De novo initiation of viral RNA-dependent RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Structure of the RNA-dependent RNA polymerase of poliovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: a dual function target for common cold antiviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

RNA synthesis in a cage--structural studies of reovirus polymerase lambda3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

A mechanism for initiating RNA-dependent RNA polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Characterization of the inhibition of hepatitis C virus RNA replication by nonnucleosides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Initiation of viral RNA-dependent RNA polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

Biochemical characterization of a hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505423200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505423200

1 reference

4 November 2017

1 reference