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The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.
scientific article published on 8 May 2006
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stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
title
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
main subject
NF-κB
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author
Dirk Brenner
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
author name string
Alexander Golks
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Peter H Krammer
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Inna N Lavrik
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
language of work or name
English
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publication date
8 May 2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
published in
Journal of Experimental Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
volume
203
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
issue
5
1 reference
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Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
page(s)
1295-1305
1 reference
stated in
Europe PubMed Central
PMC publication ID
2121210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682493%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
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PubMed Central
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Cellular FLICE-inhibitory protein is required for T cell survival and cycling
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Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation
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Requirement for caspase-8 in NF-kappaB activation by antigen receptor.
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Signaling to NF-kappaB
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27 May 2018
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway
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27 May 2018
Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort
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Interdimer processing mechanism of procaspase-8 activation.
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27 May 2018
The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation
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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
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27 May 2018
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
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FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis
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Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
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27 May 2018
Activation of the NF-kappaB pathway by caspase 8 and its homologs
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27 May 2018
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
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The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
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27 May 2018
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.
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27 May 2018
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121210
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27 May 2018
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121210
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27 May 2018
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
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27 May 2018
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
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16 June 2018
Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.
1 reference
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16 August 2018
Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
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16 August 2018
Activation interferes with the APO-1 pathway in mature human T cells.
1 reference
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PubMed Central
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Identifiers
DOI
10.1084/JEM.20051556
1 reference
stated in
Fatcat
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https://api.fatcat.wiki/v0/release/u3houwjcejc5vlbya6ebbmj2b4
retrieved
30 July 2022
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Fatcat ID
release_u3houwjcejc5vlbya6ebbmj2b4
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Fatcat
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https://api.fatcat.wiki/v0/release/u3houwjcejc5vlbya6ebbmj2b4
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30 July 2022
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mapped directly with Wikidata item
PMC publication ID
2121210
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https://api.fatcat.wiki/v0/release/u3houwjcejc5vlbya6ebbmj2b4
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PubMed publication ID
16682493
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https://api.fatcat.wiki/v0/release/u3houwjcejc5vlbya6ebbmj2b4
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ResearchGate publication ID
7099598
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