(Q42801645)

7 November 2017

Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation (English)

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7 November 2017

2

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7 November 2017

Lee TA

1

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PubMed ID

10822376

7 November 2017

language of work or name

English

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publication date

1 April 2000

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7 November 2017

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7 November 2017

19

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7 November 2017

2257-2268

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7 November 2017

18

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203556

7 November 2017

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cites work

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

The p53 proto-oncogene can act as a suppressor of transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F-3 accumulation is regulated by polypeptide stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

RAS enzyme-linked immunoblot assay discriminates p21 species: a technique to dissect gene family expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Oncogenic capacity of the E2F1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

The subcellular localization of E2F-4 is cell-cycle dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Induction of S-phase entry by E2F transcription factors depends on their nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F activity is regulated by cell cycle-dependent changes in subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

In vivo association of E2F and DP family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

E2F-1 functions in mice to promote apoptosis and suppress proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

7 January 2021

The transforming domain alone of the latent membrane protein of Epstein-Barr virus is toxic to cells when expressed at high levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

7 January 2021

An integral membrane green fluorescent protein marker, Us9-GFP, is quantitatively retained in cells during propidium iodide-based cell cycle analysis by flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

7 January 2021

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203556

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203556

1 reference

PubMed ID

10822376

Dimensions Publication ID

7 November 2017

0 references

1 reference

PubMed ID

10822376