(Q42806211)

7 November 2017

The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod. (English)

1 reference

7 November 2017

2

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7 November 2017

9

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7 November 2017

Bipin Patel

1

1 reference

7 November 2017

Audrey A Bobkov

3

1 reference

7 November 2017

L Miya Fujimoto

4

1 reference

7 November 2017

Man Zhang

5

1 reference

7 November 2017

Robert C Liddington

6

1 reference

7 November 2017

Daniela Mazzeo

7

1 reference

7 November 2017

Jonas Emsley

8

1 reference

7 November 2017

Igor L Barsukov

10

1 reference

7 November 2017

David R Critchley

11

1 reference

7 November 2017

language of work or name

English

0 references

publication date

9 January 2006

1 reference

Journal of Biological Chemistry

7 November 2017

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7 November 2017

281

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7 November 2017

7458-7467

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7 November 2017

11

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Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Tensin stabilizes integrin adhesive contacts in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

A new protein of adhesion plaques and ruffling membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Disruption of the talin gene arrests mouse development at the gastrulation stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin is essential for integrin function in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Analysis of the mammalian talin2 gene TLN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Structural determinants of integrin recognition by talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

The relationship between force and focal complex development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

The cytoskeletal protein talin contains at least two distinct vinculin binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Further characterization of the interaction between the cytoskeletal proteins talin and vinculin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Vinculin activation by talin through helical bundle conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Structural basis for amplifying vinculin activation by talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Structural basis for vinculin activation at sites of cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Sequence and domain structure of talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin at myotendinous junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Localization of talin in skeletal and cardiac muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin is a post-synaptic component of the rat neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

A role for talin in presynaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Talin concentrates to the midbody region during mammalian cell cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Characterization of two F-actin-binding and oligomerization sites in the cell-contact protein vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Characterization of an Actin-binding Site within the Talin FERM Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

Analysis of Repeated Motifs in the Talin Rod

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508058200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508058200

1 reference

7 November 2017

1 reference