(Q42808936)

7 November 2017

Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor (English)

1 reference

7 November 2017

Xu Chen

1

1 reference

PubMed ID

12397069

7 November 2017

Marilyn D Resh

series ordinal

2

1 reference

PubMed ID

12397069

7 November 2017

language of work or name

English

0 references

publication date

22 October 2002

1 reference

Journal of Biological Chemistry

7 November 2017

1 reference

7 November 2017

277

1 reference

7 November 2017

49631-49637

1 reference

7 November 2017

51

1 reference

Functional rafts in cell membranes

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Structure and function of sphingolipid- and cholesterol-rich membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Functions of lipid rafts in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Multimerization of human immunodeficiency virus type 1 Gag promotes its localization to barges, raft-like membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cellular cholesterol efflux mediated by cyclodextrins. Demonstration Of kinetic pools and mechanism of efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cellular cholesterol efflux mediated by cyclodextrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells. methyl-beta-cyclodextrin does not affect cell surface transport of a GPI-anchored protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Filipin-cholesterol complexes form in uncoated vesicle membrane derived from coated vesicles during receptor-mediated endocytosis of low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Receptor protein-tyrosine kinases and their signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cholesterol depletion induces large scale domain segregation in living cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

PC12 cells have caveolae that contain TrkA. Caveolae-disrupting drugs inhibit nerve growth factor-induced, but not epidermal growth factor-induced, MAPK phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Agonist-dependent traffic of raft-associated Ras and Raf-1 is required for activation of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Activation of Rho is required for ligand-independent oncogenic signaling by a mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Acute cholesterol depletion inhibits clathrin-coated pit budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Fluorescence lifetime imaging of receptor tyrosine kinase activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208327200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208327200

1 reference

7 November 2017

1 reference

PubMed ID

12397069