(Q42814521)

7 November 2017

Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis (English)

1 reference

7 November 2017

Herzog CR

1

1 reference

7 November 2017

Noh S

2

1 reference

7 November 2017

Lantry LE

3

1 reference

7 November 2017

Guan KL

4

1 reference

7 November 2017

You M

5

1 reference

7 November 2017

1 June 1999

1 reference

7 November 2017

Molecular Carcinogenesis

1 reference

7 November 2017

25

1 reference

7 November 2017

92-98

1 reference

7 November 2017

2

1 reference

A cell cycle regulator potentially involved in genesis of many tumor types

7 November 2017

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Mutations and altered expression of p16INK4 in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Germline p16 mutations in familial melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

How does DNA methylation repress transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Mutations associated with familial melanoma impair p16INK4 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

Inherited susceptibility to several cancers but absence of linkage between dysplastic nevus syndrome and CDKN2A in a melanoma family with a mutation in the CDKN2A ( P16INK4A ) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199906%2925%3A2%3C92%3A%3AAID-MC3%3E3.0.CO%3B2-2

10.1002/(SICI)1098-2744(199906)25:2<92::AID-MC3>3.0.CO;2-2

21 January 2018

Identifiers

DOI

1 reference

release_bv5wmwcgvbezxcwwybmx5uivmu

7 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bv5wmwcgvbezxcwwybmx5uivmu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference