(Q42815194)

7 November 2017

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization (English)

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7 November 2017

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Giannakakou P

1

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7 November 2017

Sackett DL

2

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7 November 2017

Kang YK

3

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7 November 2017

Zhan Z

4

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7 November 2017

Buters JT

5

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7 November 2017

Fojo T

6

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7 November 2017

Poruchynsky MS

7

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7 November 2017

language of work or name

English

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publication date

1 July 1997

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

272

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7 November 2017

17118-17125

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7 November 2017

27

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describes a project that uses

7 November 2017

1A9PTX10

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1A9PTX22

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cites work

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Phase II Trial of Taxol, an Active Drug in the Treatment of Metastatic Breast Cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Mechanism of action of taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Taxol stabilizes microtubules in mouse fibroblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Isolation of a taxol-resistant Chinese hamster ovary cell mutant that has an alteration in alpha-tubulin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Taxol-dependent mutants of Chinese hamster ovary cells with alterations in alpha- and beta-tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Altered expression of M beta 2, the class II beta-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Characterization of a taxol-resistant human small-cell lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

New colorimetric cytotoxicity assay for anticancer-drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Three expressed sequences within the human beta-tubulin multigene family each define a distinct isotype

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Evidence that a human beta-tubulin pseudogene is derived from its corresponding mRNA.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Are tubulin isotypes functionally significant

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Microtubule dynamics in vitro are regulated by the tubulin isotype composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Localization of the colchicine-binding site of tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Localization of the vinblastine-binding site on beta-tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Identification of the fragment photoaffinity-labeled with azidodansyl-rhizoxin as Met-363-Lys-379 on beta-tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

Tubulin sulfhydryl groups as probes and targets for antimitotic and antimicrotubule agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.27.17118

21 January 2018

Identifiers

DOI

10.1074/JBC.272.27.17118

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7 November 2017

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