(Q42829229)

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Recombinant murine gammaherpesvirus 68 (MHV-68) as challenge virus to test efficacy of vaccination against chronic virus infections in the mouse model

scientific article published on 6 March 2007

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Europe PubMed Central

PubMed publication ID

8 November 2017

Recombinant murine gammaherpesvirus 68 (MHV-68) as challenge virus to test efficacy of vaccination against chronic virus infections in the mouse model (English)

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Europe PubMed Central

PubMed publication ID

8 November 2017

5

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8 November 2017

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object named as

Caroline Staib

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8 November 2017

4

object named as

Volker Erfle

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Europe PubMed Central

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8 November 2017

author name string

Susanne El-Gogo

1

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8 November 2017

Marcus Meyr

3

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8 November 2017

Heiko Adler

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8 November 2017

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6 March 2007

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8 November 2017

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12

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8 November 2017

25

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8 November 2017

20

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8 November 2017

3934-3945

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Europe PubMed Central

PubMed publication ID

8 November 2017

Strategies and mechanisms for host and pathogen survival in acute and persistent viral infections

1 reference

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Old and new vaccine approaches

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Immunology of hepatitis B virus and hepatitis C virus infection

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Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis

1 reference

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Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis

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Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection

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Vaccination against murine gamma-herpesvirus infection

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Immune evasion by gamma-herpesviruses

1 reference

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Immune mechanisms in murine gammaherpesvirus-68 infection.

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Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8).

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Natural history of murine -herpesvirus infection

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A battle for survival: immune control and immune evasion in murine gamma-herpesvirus-68 infection.

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Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo

1 reference

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Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages

1 reference

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Lung epithelial cells are a major site of murine gammaherpesvirus persistence

1 reference

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Long-term latent murine Gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo

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Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells

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Selective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes

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Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells

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Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome

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Infectious clones of herpesviruses: a new approach for understanding viral gene function

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MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA) (author's transl)

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Nonreplicating vaccinia vector efficiently expresses recombinant genes

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Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line

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Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells

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Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine

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Vaccinia vectors as candidate vaccines: the development of modified vaccinia virus Ankara for antigen delivery

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Therapeutic vaccination with MVA-HIV-1 nef elicits Nef-specific T-helper cell responses in chronically HIV-1 infected individuals

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Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

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Therapeutic vaccination with MVA E2 can eliminate precancerous lesions (CIN 1, CIN 2, and CIN 3) associated with infection by oncogenic human papillomavirus

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Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

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Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma

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Immunization of Patients with Malignant Melanoma with Autologous CD34+ Cell-Derived Dendritic Cells Transduced Ex Vivo with a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial

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Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

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A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults

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Safety and immunogenicity of DNA/modified vaccinia virus ankara malaria vaccination in African adults

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A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans

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Transient host range selection for genetic engineering of modified vaccinia virus Ankara

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Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence

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Virus reconstituted from infectious bacterial artificial chromosome (BAC)-cloned murine gammaherpesvirus 68 acquires wild-type properties in vivo only after excision of BAC vector sequences

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An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection

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An optimized CD8+ T-cell response controls productive and latent gammaherpesvirus infection

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Gamma-herpesvirus latency requires T cell evasion during episome maintenance

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Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection

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Postexposure vaccination massively increases the prevalence of gamma-herpesvirus-specific CD8+ T cells but confers minimal survival advantage on CD4-deficient mice

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10.1016/J.VACCINE.2007.02.054

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

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