(Q42834737)

8 November 2017

Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength (English)

1 reference

8 November 2017

B C Duckworth

1

1 reference

PubMed ID

9346906

8 November 2017

L C Cantley

series ordinal

2

1 reference

PubMed ID

9346906

8 November 2017

language of work or name

English

0 references

publication date

1 October 1997

1 reference

Journal of Biological Chemistry

8 November 2017

1 reference

8 November 2017

272

1 reference

8 November 2017

27665-27670

1 reference

8 November 2017

44

1 reference

Oncogenes and signal transduction

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Alpha1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. Role in mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Wortmannin inhibits mitogen-activated protein kinase activation by platelet-activating factor through a mechanism independent of p85/p110-type phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Complex formation between RAS and RAF and other protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

Wortmannin inhibits the activation of MAP kinase following vasopressin V1 receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.44.27665

21 January 2018

Identifiers

DOI

10.1074/JBC.272.44.27665

1 reference

8 November 2017

1 reference

PubMed ID

9346906