(Q43455466)

23 November 2017

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. (English)

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23 November 2017

2

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23 November 2017

Yoji Andrew Minamishima

3

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23 November 2017

Qing Zhang

4

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William G. Kaelin

8

object named as

William G Kaelin

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23 November 2017

7

Sabina Signoretti

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23 November 2017

Arthur P Young

1

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23 November 2017

Lianjie Li

5

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23 November 2017

Chiara Grisanzio

6

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23 November 2017

24 February 2008

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23 November 2017

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23 November 2017

10

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23 November 2017

361-369

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23 November 2017

3

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https://scigraph.springernature.com/pub.10.1038/ncb1699

23 November 2017

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cites work

Von Hippel-Lindau disease.

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The thorny path linking cellular senescence to organismal aging

21 January 2018

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Intrinsic tumour suppression

21 January 2018

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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Tumour biology: senescence in premalignant tumours

21 January 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

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Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

21 January 2018

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

21 January 2018

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Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.

21 January 2018

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Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

21 January 2018

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Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo

21 January 2018

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Cellular senescence: mitotic clock or culture shock?

21 January 2018

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Tissue-specific inactivation of p53 tumor suppression in the mouse.

21 January 2018

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Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

21 January 2018

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Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

21 January 2018

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

21 January 2018

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Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins

21 January 2018

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The p400 complex is an essential E1A transformation target

21 January 2018

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p400 is required for E1A to promote apoptosis

21 January 2018

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The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway

21 January 2018

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HIF1alpha delays premature senescence through the activation of MIF.

21 January 2018

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HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

21 January 2018

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Telomerase maintains telomere structure in normal human cells.

21 January 2018

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Hypoxia inhibits G1/S transition through regulation of p27 expression

21 January 2018

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7 January 2021

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

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7 January 2021

Kip1 meets SKP2: new links in cell-cycle control

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7 January 2021

Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth

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7 January 2021

Identifiers

DOI

10.1038/NCB1699

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23 November 2017

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