(Q43540745)

English

Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.

scientific article published in March 2001

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scholarly article

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5 November 2019

Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity (English)

1 reference

Europe PubMed Central

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5 November 2019

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Carsten Culmsee

1

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5 November 2019

author name string

S Bondada

2

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5 November 2019

M P Mattson

3

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5 November 2019

publication date

1 March 2001

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5 November 2019

Molecular Brain Research

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5 November 2019

87

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5 November 2019

257-262

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5 November 2019

2

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5 November 2019

DNA strand breaks in Alzheimer's disease.

1 reference

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7 January 2021

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The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

1 reference

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7 January 2021

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

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7 January 2021

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Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1 reference

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7 January 2021

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DNA-dependent protein kinase-independent activation of p53 in response to DNA damage

1 reference

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7 January 2021

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

1 reference

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Activation of DNA-dependent protein kinase may play a role in apoptosis of human neuroblastoma cells.

1 reference

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7 January 2021

based on heuristic

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Excitotoxic cell death

1 reference

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7 January 2021

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Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain

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Pathobiology of ischaemic stroke: an integrated view

1 reference

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7 January 2021

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The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

1 reference

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7 January 2021

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Mitochondria and apoptosis

1 reference

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7 January 2021

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

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7 January 2021

based on heuristic

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DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase

1 reference

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7 January 2021

based on heuristic

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DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

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7 January 2021

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Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

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7 January 2021

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Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

1 reference

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7 January 2021

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The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight

1 reference

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7 January 2021

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Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

1 reference

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7 January 2021

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Apoptosis and expression of DNA repair proteins in ischaemic brain injury in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

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Recent advances on neuronal caspases in development and neurodegeneration

1 reference

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7 January 2021

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Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons

1 reference

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7 January 2021

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Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

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Apoptosis in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptotic and antiapoptotic mechanisms in stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

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Poly (ADP-ribose) polymerase, nitric oxide and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

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Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

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Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.

1 reference

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7 January 2021

based on heuristic

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Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2801%2900008-0

7 January 2021

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Bax involvement in p53-mediated neuronal cell death

1 reference

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Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

1 reference

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Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

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7 January 2021

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inferred from DOI database lookup

Stimulation of beta2-adrenoceptors inhibits apoptosis in rat brain after transient forebrain ischemia.

1 reference

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Identifiers

10.1016/S0169-328X(01)00008-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11245929%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11245929%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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