(Q43693180)

English

Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity

scientific article published on 31 July 2001

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 November 2017

Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity (English)

1 reference

Europe PubMed Central

25 November 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

25 November 2017

6

object named as

Hemmings BA

1 reference

Europe PubMed Central

25 November 2017

author name string

Hill MM

2

1 reference

Europe PubMed Central

25 November 2017

Hess D

3

1 reference

Europe PubMed Central

25 November 2017

Brazil DP

4

1 reference

Europe PubMed Central

25 November 2017

Hofsteenge J

5

1 reference

Europe PubMed Central

25 November 2017

language of work or name

0 references

publication date

31 July 2001

1 reference

Europe PubMed Central

25 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

25 November 2017

276

1 reference

Europe PubMed Central

25 November 2017

37459-37471

1 reference

Europe PubMed Central

25 November 2017

40

1 reference

Europe PubMed Central

25 November 2017

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

PDK1, one of the missing links in insulin signal transduction?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Intracellular signalling: PDK1--a kinase at the hub of things

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Mechanism of protein kinase B activation by insulin/insulin-like growth factor-1 revealed by specific inhibitors of phosphoinositide 3-kinase--significance for diabetes and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Kinase phosphorylation: Keeping it all in the family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Cellular signaling: pivoting around PDK-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Characterization of S6K2, a novel kinase homologous to S6K1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Akt signaling: linking membrane events to life and death decisions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The akt kinase: molecular determinants of oncogenicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Analytical properties of the nanoelectrospray ion source

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The IRS-signalling system during insulin and cytokine action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

The carboxyl terminus of protein kinase c provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Regulation of protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105916200

21 January 2018

Identifiers

10.1074/JBC.M105916200

1 reference

Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43693180&oldid=2102624154"