(Q43729271)

26 November 2017

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice (English)

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26 November 2017

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Krimpenfort P

1

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26 November 2017

Quon KC

2

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26 November 2017

Mooi WJ

3

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26 November 2017

Loonstra A

4

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26 November 2017

Berns A

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26 November 2017

language of work or name

English

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publication date

1 September 2001

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26 November 2017

4

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inferred from page(s)

published in

Nature

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26 November 2017

413

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26 November 2017

83-86

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26 November 2017

6851

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https://scigraph.springernature.com/pub.10.1038/35092584

26 November 2017

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cites work

Tumor surveillance via the ARF-p53 pathway.

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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7 January 2021

The INK4A/ARF locus and its two gene products

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7 January 2021

Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

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7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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7 January 2021

Cellular senescence as a tumor-protection mechanism: the essential role of counting

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

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7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

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7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

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7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

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7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

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7 January 2021

Differential expression of p16INK4a and p16beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations.

1 reference

7 January 2021

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

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7 January 2021

Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer

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7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

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7 January 2021

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

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7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

7 January 2021

Identifiers

DOI

10.1038/35092584

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Dimensions Publication ID

26 November 2017

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